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Abstract book 6th RMS 16.indd

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symptoms, half of our patients needed<br />

DMARDs as well. Unlike other series, we<br />

had no cases of large joint episodic arthritis<br />

or cases of HPOA. Instead, our patient<br />

showed an RA like polyarthritis (small and<br />

large joints) with an age of onset of 25 in<br />

females and 38 in men.<br />

In addition to NSAIDs, DMARDs are often<br />

needed.<br />

There should be a low threshold for referral<br />

to a rheumatologist because the arthritis<br />

and limitation of movement may become<br />

disabling and interfere with mobility,<br />

exercise and chest clearance, all essential<br />

components of CF daily treatment routine.<br />

96<br />

Antiphospholipid Syndrome and<br />

Pregnancy<br />

Olivier Bletry MD (France)<br />

97<br />

Lupus Nephritis at King Hussein<br />

Medical Center<br />

Auasyalah Burgan MD*, Manal Al-Mashalah<br />

MD, Osma Katybah MD, Ala’a Al-Heresh MD<br />

* Rheumatology Division, King Hussein Medical<br />

Center, Royal Medical Services (Jordan)<br />

ausaylah2@hotmail.com<br />

Objectives: Renal involvement is a serious<br />

feature of systemic Lupus Erythmatosus.<br />

It has been shown that the decision to<br />

institute therapy is highly informed by the<br />

results of renal biopsy We present the first<br />

review of lupus nephritis in KHMC, and we<br />

compare our findings with other studies.<br />

Methods: We retrospectively reviewed<br />

medical records and renal slides of 74<br />

patients over a 14 year period (1996‐2009).<br />

the renal biopsy specimens were studied by<br />

light and immunofluorescence microscopy.<br />

Results: 74 patients were reviewed, 69<br />

(93.24%) were females and 5 (6.75%)<br />

were males. The female to male ratio was<br />

(13.8:1).The median age was 26 year.<br />

The indications for renal biopsy were the<br />

presence of proteinuria, defined as a 24 hr<br />

urinary protein excretion on presentation<br />

0.5g and/or the presence of active casts in<br />

the urinary sediment. Diffuse proliferative<br />

glomerulonephritis (class IV) was the<br />

most frequent histopathologic finding in<br />

our patients seen in 30 patients (40.1%).<br />

The frequencies of other histopathologic<br />

findings were as follows: Class III (n=10,<br />

13.5%), Class V (n =7, 9.5%), Class I (n =6,<br />

8.1%), class II (n=1, 1.3%). All the patients<br />

were treated with different combination<br />

of treatment. All patients were followed<br />

up, 2 died . 58 patients had controlled<br />

disease, 11 still having active disease, and<br />

4 patients on chronic hemodiaysis, one of<br />

them had kidney transplant.<br />

Conclusion: Diffuse proliferative GN class<br />

IV was the most frequent type of lupus<br />

nephritis in the world as in this study.<br />

Hall E Session 3<br />

Pulmonology & Thoracic Surgery<br />

98<br />

Flail Chest Wall Stabilization<br />

Michael Mueller MD (Austria)<br />

The morbidity of serial rib fractures is often<br />

underestimated. A retrospective analysis<br />

of 181 331 patients after car accidents<br />

using the US National Trauma Databank<br />

revealed that 55% of patients over 60<br />

years dying after chest trauma had no<br />

more than rib fractures. Patients over the<br />

age of 45 years with more than four rib<br />

fractures are more severely injured and at<br />

increased risk of adverse outcomes. Hence,<br />

efforts to decrease rib fracture morbidity<br />

should focus not only on elderly patients<br />

but those as young as 45 years.<br />

Serial rib fractures have effects on the<br />

chest wall with loss of rigidity, paradoxical<br />

motion and the consequence of ineffective<br />

cough, as well as effects on the lungs<br />

including hypoventilation, contusion and<br />

resulting hypoxemia.<br />

When deciding on the optimal treatment<br />

of serial rib fractures with flail segments<br />

the conservative approach with internal<br />

pneumatic stabilization had been<br />

evaluated as an alternative to surgical<br />

approaches. Relevant recent literature<br />

clearly demonstrates superiority of surgical<br />

stabilization over pneumatic stabilization<br />

regarding incidence of pneumonia, length<br />

of ICU stay, length of mechanical ventilation<br />

and requirement of tracheostomy.<br />

The indication for surgical stabilization<br />

can be considered along with a routine<br />

emergency repair when closing a<br />

thoracotomy, or electively at the presence<br />

of poor pain control, chest wall instability<br />

and the risk for respiratory failure or to<br />

75 www.jrms.gov.jo

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