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Intravenous anaesthetic-hypnotic drugs Propofol Pentothal ...

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25/11/2010<br />

Etomidate / Administration<br />

Available as a solution in propylene glycol.<br />

l<br />

An IV induction dose is 0.3 mg/kg.<br />

Etomidate / Side effects<br />

a. Myoclonus may occur after administration,<br />

particularly in response to stimulation.<br />

b. Nausea and vomiting occur more frequently in the<br />

postoperative period than with other anesthetic agents.<br />

c. Venous irritation may be minimized by administration<br />

into a free-flowing IV carrier infusion.<br />

d. Adrenal suppression<br />

Suppresses adrenal steroid synthesis for up to 24<br />

hours (probably an effect of little clinical significance).<br />

Repeated doses or infusions are not recommended<br />

because of the risk of significant adrenal suppression.<br />

21

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