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4 th <strong>Euregio</strong> <strong>Conference</strong><br />

<strong>of</strong><br />

<strong>Clinical</strong> <strong>Chemistry</strong> <strong>and</strong> <strong>Laboratory</strong><br />

Medicine<br />

Maastricht-Aachen-Liège<br />

Friday 14 th March 2008<br />

University Hospital Maastricht<br />

Greep lecture-room, 4 th floor<br />

The conference takes place under the<br />

auspices <strong>of</strong>:<br />

• The Dutch Association for <strong>Clinical</strong><br />

<strong>Chemistry</strong> <strong>and</strong> <strong>Laboratory</strong> Medicine (<strong>NVKC</strong>)<br />

<strong>and</strong><br />

• European Federation <strong>of</strong> <strong>Clinical</strong> <strong>Chemistry</strong><br />

<strong>and</strong> <strong>Laboratory</strong> Medicine (EFCC)<br />

<strong>Euregio</strong> Committee <strong>Clinical</strong> <strong>Chemistry</strong> <strong>and</strong> <strong>Laboratory</strong> Medicine<br />

Listed with accreditation points in each country


Speakers <strong>and</strong> Chairpersons:<br />

• Althaus, H. dr. - Siemens Healthcare Diagnostics - Marburg (D)<br />

harald.althaus@siemens.com<br />

• Bakker, J.A. drs. - Maastricht (NL)<br />

jbak@klinchem.azm.nl<br />

• Bekers, O. dr. - Maastricht (NL)<br />

obe@klinchem.azm.nl<br />

• Campenhout, C. van, dr. - Brussels (B)<br />

Christel.vancampenhout@iph.fgov.be<br />

• Chapelle, J.P. pr<strong>of</strong>. dr. - Liège (B)<br />

JP.Chapelle@che.ulg.ac.be<br />

• Cobbaert, C. dr. - Breda (NL)<br />

christa@cobbaert.nl<br />

• Dieijen-Visser, M.P. van, pr<strong>of</strong>. dr. - Maastricht (NL)<br />

dieijen@klinchem.azm.nl<br />

• Götting, C. dr. PD - Bad Oeynhausen (D)<br />

cgoetting@hdz-nrw.de<br />

• Gressner, A.M. pr<strong>of</strong>. dr. med. - Aachen (D)<br />

agressner@ukaachen.de<br />

• Herrmann, W. pr<strong>of</strong>. dr. med. habil. dr. rer. nat. - Homburg (D)<br />

pr<strong>of</strong>.wolfgang.herrmann@uniklinikum-saarl<strong>and</strong>.de<br />

• Jacobs, L.H.J. drs. - Maastricht (NL)<br />

L.Jacobs@lche.azm.nl<br />

• Luppa, P.B. pr<strong>of</strong>. dr. - München (D)<br />

luppa@klinchem.med.tum.de<br />

• Lutteri L. phar. biol. - Liège (B)<br />

laurence.lutteri@chu.ulg.ac.be<br />

• Mingels, A.M.A. ir. - Maastricht (NL)<br />

A.Mingels@klinchem.azm.nl<br />

• Scheen, A. pr<strong>of</strong>. dr. - Liège (B)<br />

<strong>and</strong>re.scheen@che.ulg.ac.be<br />

• Vossen, R.C.R.M. dr. - Sittard (NL)<br />

r.vossen@orbisconcern.nl<br />

• Wodzig, W.K.W.H. dr. - Maastricht (NL)<br />

kwo@lche.azm.nl


Introduction<br />

On behalf <strong>of</strong> the organizing committee it is our great pleasure to invite you for<br />

the 4 th <strong>Euregio</strong> <strong>Conference</strong> <strong>of</strong> <strong>Clinical</strong> <strong>Chemistry</strong> <strong>and</strong> <strong>Laboratory</strong> Medicine.<br />

After three successful <strong>Euregio</strong> conferences, alternately organized by one <strong>of</strong> the<br />

university hospitals <strong>of</strong> Maastricht-Liège-Aachen, we decided to start a new<br />

cycle <strong>of</strong> conferences. The 4 th <strong>Euregio</strong> conference will be organized by the<br />

University Hospital <strong>of</strong> Maastricht on March, 14 th in Maastricht. The conferences<br />

give us the opportunity to inform each other upon scientific activities at the<br />

different sites <strong>and</strong> have become an important educational activity.<br />

We again hope to <strong>of</strong>fer an interesting program.<br />

The program in three sessions is focused on point <strong>of</strong> care testing, metabolic<br />

disease <strong>and</strong> finally a session on test st<strong>and</strong>ardization <strong>and</strong> harmonization.<br />

We are sure that all participants will benefit from the academic exchanges <strong>and</strong><br />

personal contacts. We are looking forward to seeing you in Maastricht.<br />

We wish you a fruitful <strong>and</strong> enjoyable day in Maastricht.<br />

Pr<strong>of</strong>. dr. M.P. van Dieijen-Visser<br />

On behalf <strong>of</strong> the <strong>Euregio</strong> Committee on <strong>Clinical</strong> <strong>Chemistry</strong> <strong>and</strong> <strong>Laboratory</strong><br />

Medicine


Program <strong>of</strong> the 4 th <strong>Euregio</strong> <strong>Conference</strong> <strong>of</strong> <strong>Clinical</strong> <strong>Chemistry</strong> <strong>and</strong><br />

<strong>Laboratory</strong> Medicine (March 14 th 2008)<br />

09.00 – 09.30 Arrival, registration <strong>and</strong> wake-up c<strong>of</strong>fee<br />

09.30 – 09.40 Opening <strong>and</strong> Welcome to the 4 th <strong>Euregio</strong> <strong>Conference</strong><br />

by pr<strong>of</strong>. dr. M.P. van Dieijen-Visser, Maastricht<br />

Metabolic disease<br />

Chairperson: A. Gressner<br />

09.40 - 10.00 Mitochondrial DNA depletion syndromes due to autosomal<br />

defects in purine <strong>and</strong> pyrimidine metabolism.<br />

J.A. Bakker, Maastricht<br />

10.00 - 10.20 Advances in obesity: adipose tissue as an endocrine <strong>and</strong><br />

inflammatory organ.<br />

A. Scheen, Liège<br />

10.20 – 10.50 Hyperhomocysteinemia <strong>and</strong> degenerative diseases.<br />

W. Herrmann, Homburg<br />

10.50 – 11.20 C<strong>of</strong>fee/tea break<br />

Point <strong>of</strong> care testing<br />

Chairperson: J.P. Chapelle<br />

11.20 – 11.40 External evaluation <strong>of</strong> quality <strong>of</strong> POCT glucose - 2 years <strong>of</strong><br />

experience in Belgium.<br />

C. van Campenhout, Brussels<br />

11.40 – 12.00 Network-based quality program for hospital Point-Of-Care-<br />

Testing, analytical <strong>and</strong> organisational remarks.<br />

P.B. Luppa, Munich<br />

12.00 – 12.15 <strong>Laboratory</strong> responsibilities <strong>and</strong> POC-testing.<br />

O. Bekers, Maastricht<br />

12.15 – 12.30 Pitfalls in glucose point <strong>of</strong> care testing.<br />

R.C.R.M. Vossen, Sittard


12.30 – 13.30 Lunch Buffet<br />

Test st<strong>and</strong>ardization <strong>and</strong> harmonization<br />

Chairpersons: W. Wodzig <strong>and</strong> M.P. van Dieijen-Visser<br />

13.30 – 13.50 Harmonization <strong>of</strong> troponin assays: an illusion.<br />

C. Cobbaert, Breda<br />

13:50 14:05 Implications <strong>of</strong> high sensitive troponin assays.<br />

A.M.A. Mingels, Maastricht<br />

14:05 - 14:20 High sensitive troponin in end stage renal disease.<br />

L.H.J. Jacobs, Maastricht<br />

14.20 – 14.50 St<strong>and</strong>ardization <strong>of</strong> glycated haemoglobin measurement:<br />

diabetes under control.<br />

C. Götting, Bad Oeynhausen<br />

14.50 – 15.20 C<strong>of</strong>fee/tea break<br />

Test st<strong>and</strong>ardization <strong>and</strong> harmonization (continued)<br />

Chairpersons: W. Wodzig <strong>and</strong> M.P. van Dieijen-Visser<br />

15.20 – 15.40 Improving st<strong>and</strong>ardization <strong>of</strong> immunoassays for anti-cyclic<br />

citrullinated peptide (anti-ccp) antibodies.<br />

L. Lutteri, Liège<br />

15.40 – 16.00 St<strong>and</strong>ardisation <strong>of</strong> plasma proteins, past, present <strong>and</strong> a few<br />

into the future<br />

H. Althaus, Marburg<br />

16.00 Conclusions <strong>and</strong> Closing Remarks<br />

by pr<strong>of</strong>. dr. M.P. van Dieijen-Visser<br />

<strong>and</strong><br />

16:10 Invitation to the 5 th <strong>Euregio</strong> <strong>Conference</strong> 2009 in Liège (B)<br />

by pr<strong>of</strong>. dr. J.P. Chapelle<br />

16:15 Get-together / Departure


Location<br />

The conference location is the University Hospital <strong>of</strong> Maastricht, in the Greep<br />

lecture-room (4.01) on the fourth floor.<br />

For more information <strong>and</strong> registration contact<br />

Pr<strong>of</strong>. dr. M.P. van Dieijen-Visser<br />

University Hospital Maastricht (NL)<br />

dieijen@klinchem.azm.nl<br />

Tel. + 31 43 3874694 or 3876694<br />

Fax. + 31 43 3874667<br />

Participation <strong>and</strong> Payment<br />

Registration can be submitted using the enclosed registration form <strong>and</strong> send to:<br />

L. Paffen-Hovens, Dept. <strong>Clinical</strong> <strong>Chemistry</strong>, University Hospital Maastricht, P.O.<br />

Box 5800, 6202 AZ Maastricht, The Netherl<strong>and</strong>s, or by sending the mentioned<br />

information by E-mail to LPAF@klinchem.azm.nl, or Fax: +31 43 3874667.<br />

The registration fee amounts € 25,-. The registration fee can be paid by Bank<br />

transfer to: “Ver Klinisch Chemici Limburg, Maastricht, Swiftcode: PSTBNL21,<br />

IBAN: NL85 PSTB 0006 9303 13”. Please mention the name <strong>of</strong> the<br />

participant(s). After March 1, 2008 no reimbursements are made.<br />

<strong>Euregio</strong> Committee <strong>Clinical</strong> <strong>Chemistry</strong> <strong>and</strong> <strong>Laboratory</strong> Medicine<br />

Pr<strong>of</strong>. dr. M.P. van Dieijen-Visser<br />

Dr. W.K.W.H. Wodzig<br />

Dept. <strong>of</strong> <strong>Clinical</strong> <strong>Chemistry</strong>, University Hospital, Maastricht, NL<br />

Pr<strong>of</strong>. dr. med. A.M. Gressner<br />

Dr. E. Yagmur<br />

Inst. <strong>of</strong> <strong>Clinical</strong> <strong>Chemistry</strong> <strong>and</strong> Pathobiochemistry, University Hospital,<br />

Aachen, D<br />

Pr<strong>of</strong>. dr. J.P. Chapelle<br />

Dr. J. Collette<br />

Dept. <strong>of</strong> <strong>Clinical</strong> <strong>Chemistry</strong>, University Hospital, Liège, B


Itinerary<br />

University Hospital Maastricht (azM)<br />

Visiting address<br />

P. Debyelaan 25<br />

6229 HX Maastricht<br />

Public transportation<br />

By train<br />

You can get to the azM by train (via train station R<strong>and</strong>wijck) with the slow<br />

trains Sittard-Maastricht <strong>and</strong> Heerlen-Maastricht as well as the intercity train<br />

Maastricht-Liège-Knokke.<br />

By bus<br />

You can get to the azM by bus with the cross-town buslines: 1, 3, 4,9 <strong>and</strong> 11,<br />

the evening cross-town buslines: 21, 22, 24 <strong>and</strong> 28 as well as the regional<br />

buslines: 53, 56, 57, 58 <strong>and</strong> 59. All mentioned busses leave from the central<br />

train station to the azM. Visitors who use other buslines need to transfer to<br />

one <strong>of</strong> these lines at the central train station.<br />

Visitors who come by bus or taxi/cab can use the west side (Westzijde)<br />

entrance <strong>of</strong> the hospital. Busses <strong>and</strong> taxi/cabs stop underneath the azM’s<br />

visitors restaurant there.<br />

The cross-town busses 1 (to De Heeg), 3 (to Maasveld), 4 (to R<strong>and</strong>wijck-azM),<br />

9 (to Heugem), <strong>and</strong> the evening/night busses 21 (to Heugem-Maasveld) <strong>and</strong> 28<br />

(to De Heeg) as well as the Arriva-buslines 56 (to Gulpen), 57 (to Gulpen) <strong>and</strong><br />

59 (to Mesch). All busses leave directly from the central train station to the<br />

azM. Visitors who use other bus lines need to transfer to one <strong>of</strong> these lines at<br />

the central train station.<br />

By car<br />

You can get to the azM by car via the A2 motorway, direction Liège-Luik.<br />

Please follow the signs that say “academisch ziekenhuis”, “ac. Zkhs.”, “H” or<br />

“azM”.<br />

Parking space at the azM is limited. For a small fee visitors can use the parking<br />

decks on the south side (Zuidzijde) <strong>of</strong> the building. These decks are connected<br />

to the hospital’s entrance via a covered footbridge.<br />

Special parking spaces for the disabled are reserved on the top two parking<br />

decks.

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