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purcc 2012 - University of the Pacific

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Oral Presentation Abstracts<br />

For this paper I employ biographical information<br />

about Shirin Neshat in order to show how her<br />

upbringing influenced her vision <strong>of</strong> <strong>the</strong> separate<br />

spheres for men and women. This is<br />

supplemented by a consideration <strong>of</strong> <strong>the</strong> cultural,<br />

social, and religious codes in Muslim countries,<br />

in particular Iran. I also examine <strong>the</strong> gender roles<br />

<strong>of</strong> men and women in <strong>the</strong> Muslim world, which<br />

clarify that, through her work, Neshat is trying<br />

to convey her belief that despite women’s<br />

limited rights, <strong>the</strong>y still have a powerful voice.<br />

Finally, I conduct a formal analysis <strong>of</strong> <strong>the</strong> video<br />

in order to show that despite <strong>the</strong>ir separation, <strong>the</strong><br />

fate <strong>of</strong> men and women are<br />

powerfully linked.<br />

TDS, not so tedious: An efficient<br />

technique to study topological changes in<br />

modified G-quadruplex DNA<br />

Arlen Guillen<br />

Faculty mentor: Liang Xue<br />

The UV <strong>the</strong>rmal difference spectrum (TDS) is a<br />

convenient and inexpensive tool for<br />

characterization <strong>of</strong> nucleic acid structures. It is<br />

obtained by taking <strong>the</strong> difference in <strong>the</strong> UV<br />

absorbance spectra <strong>of</strong> <strong>the</strong> unfolded and folded<br />

states <strong>of</strong> a given nucleic acid below and above its<br />

melting temperature. The specific shape <strong>of</strong> <strong>the</strong><br />

spectra is distinctive for a given nucleic acid<br />

sequence/structure. Recently, it was reported<br />

(Angew. Chem. Int. Ed. 2011, 123, 10833-10836)<br />

that TDS spectra can be used to classify different<br />

types <strong>of</strong> G-quadruplex DNA topologies as well.<br />

G-quadruplex DNA is a unique DNA secondary<br />

structure that is formed by guanine rich nucleic<br />

acid sequences. The guanine nucleobase can<br />

associate through Hoogsteen hydrogen bonds to<br />

form a square planar structure called G-tetrad.<br />

The G-tetrads <strong>the</strong>n stack on top <strong>of</strong> each o<strong>the</strong>r to<br />

give rise to G-quadruplex DNA. Such structures<br />

have been proposed to form at <strong>the</strong> ends <strong>of</strong><br />

chromosomes i.e. <strong>the</strong> telomeric region containing<br />

<strong>the</strong> 5’-dTTAGGG repeats and play an important<br />

role in genomic integrity. Telomeric DNA is<br />

readily accessible by DNA damaging agents,<br />

leading to chemical modification <strong>of</strong> nucleobases<br />

such as 8-oxo-7,8-dihydroguanine (8-oxodG), 8-<br />

oxo-7,8-dihydroadenine (8-oxodA) and abasic<br />

sites. Herein, we report <strong>the</strong> use <strong>of</strong> TDS as a tool<br />

to study <strong>the</strong> effect <strong>of</strong> location and type <strong>of</strong><br />

nucleobase modification viz. 8-oxodG, 8-oxodA<br />

and abasic sites, on <strong>the</strong> topological changes in G-<br />

quadruplex DNA structures.<br />

Student Self Esteem's Effect on<br />

Classroom Leadership<br />

Chelsea Fredrick<br />

Faculty Mentor: Qingwen Dong<br />

It is assumed that student’s who possess <strong>the</strong><br />

combination <strong>of</strong> high self-esteem and social<br />

intelligence are guaranteed to be more vocal,<br />

persuasive, and productive leaders within a<br />

classroom environment and later in <strong>the</strong> work<br />

environment. However, without statistical data it<br />

is difficult to prove <strong>the</strong> correlation between a<br />

student’s self confidence and <strong>the</strong>ir performance<br />

within <strong>the</strong> classroom. This paper intends to<br />

present data that will clearly define <strong>the</strong> influence<br />

individual self esteem and social intelligence has<br />

over classroom behavior. After assessing<br />

individual empathy, listening skills, open<br />

mindedness, productivity, and persuasion<br />

techniques within <strong>the</strong> classroom, this information<br />

can be compared to each student’s semantic<br />

differential scale (a classic self esteem survey).<br />

After testing is complete, each personality<br />

quality will be tested for reliability and <strong>the</strong>n<br />

continue on to a complete correlation analysis.<br />

The final statistics presented will give a vivid<br />

indication <strong>of</strong> <strong>the</strong> relationship between <strong>the</strong><br />

mentality <strong>of</strong> a student and how <strong>the</strong>y conduct<br />

<strong>the</strong>mselves within a learning environment.<br />

Call <strong>of</strong> Duty: Affects <strong>of</strong> Violent Video<br />

Games on Aggressive Behaviors<br />

Gabriella Giannini<br />

Faculty Mentor: Qingwen Dong<br />

The impact <strong>of</strong> chronic violent video game play<br />

on player’s aggressive behaviors have been a<br />

passionate debate with mixed results supporting<br />

both sides <strong>of</strong> <strong>the</strong> issue. For over 40 years, violent<br />

video games have been able to efficiently market<br />

its violent plot and images to millions <strong>of</strong> players<br />

even in a market inundated with competition.<br />

Call <strong>of</strong> Duty, one <strong>of</strong> <strong>the</strong> most popular violent<br />

video games in <strong>the</strong> contemporary marketplace is<br />

a game that motivates its players to take on <strong>the</strong><br />

role <strong>of</strong> military arms men and kill as many<br />

competitors as possible. This game has gained<br />

widespread appeal, even with a strong M-rating<br />

(mature) that advises consumers <strong>of</strong> its graphic<br />

storyline, characters, and weaponry. With this<br />

pervasive attraction to violence in video games,<br />

<strong>the</strong> possibility <strong>of</strong> players subconsciously<br />

retaining <strong>the</strong> violent action and images shown in<br />

<strong>the</strong> violent video games is a serious possibility.<br />

Through a sample <strong>of</strong> 300 college students, this<br />

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