Clinical Guidelines for Acute Stroke Management - Living on the EDge
Clinical Guidelines for Acute Stroke Management - Living on the EDge
Clinical Guidelines for Acute Stroke Management - Living on the EDge
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Secti<strong>on</strong> 7 Sec<strong>on</strong>dary Preventi<strong>on</strong><br />
evidence <strong>on</strong> interventi<strong>on</strong>s to increase fitness. 389<br />
Exercise has clear benefits <str<strong>on</strong>g>for</str<strong>on</strong>g> reducing<br />
hypertensi<strong>on</strong> in at-risk people 390 and improving<br />
glycemic c<strong>on</strong>trol <str<strong>on</strong>g>for</str<strong>on</strong>g> those with type 2 diabetes. 391<br />
Thus increasing exercise, particularly aerobic<br />
exercise, could be expected to reduce <strong>the</strong> risk of<br />
fur<strong>the</strong>r stroke.<br />
> Excessive alcohol c<strong>on</strong>sumpti<strong>on</strong> increases <strong>the</strong> risk of<br />
stroke, 392 so reducing alcohol levels could be<br />
expected to modify <strong>the</strong> risk of fur<strong>the</strong>r strokes.<br />
However, light alcohol intake was found to be<br />
protective of stroke events. 392 The NHMRC Dietary<br />
<str<strong>on</strong>g>Guidelines</str<strong>on</strong>g> <str<strong>on</strong>g>for</str<strong>on</strong>g> Australian Adults 2003 recommend<br />
limiting alcohol c<strong>on</strong>sumpti<strong>on</strong> to a daily level of 2<br />
standard drinks <str<strong>on</strong>g>for</str<strong>on</strong>g> men and 1 standard drink <str<strong>on</strong>g>for</str<strong>on</strong>g><br />
women. 384<br />
> A multifactorial behavioural interventi<strong>on</strong> strategy<br />
may be required that targets several risk factors.<br />
One study found a program of initiating tailored<br />
sec<strong>on</strong>dary preventi<strong>on</strong>, including lifestyle<br />
interventi<strong>on</strong>s, while in hospital lead to improved<br />
rates of adherence both prior to discharge and<br />
3 m<strong>on</strong>ths after discharge. 393, 394 Every stroke<br />
survivor was given lifestyle advice and good<br />
adherence was achieved regarding diet (78%),<br />
exercise (70%) and smoking cessati<strong>on</strong> (83% of<br />
previous smokers had quit). 394 O<strong>the</strong>r educati<strong>on</strong>al<br />
interventi<strong>on</strong>s have also reported improved<br />
adherence to dietary advice. 59, 60 Systematic<br />
reviews have also found behaviour techniques,<br />
<str<strong>on</strong>g>for</str<strong>on</strong>g> example dietary or motivati<strong>on</strong>al counseling,<br />
provided by a specialist, trained clinician is effective<br />
at changing behaviour in primary care setting.<br />
395, 396<br />
Lifescripts is a nati<strong>on</strong>al initiative, which provides<br />
tools <str<strong>on</strong>g>for</str<strong>on</strong>g> primary care clinicians promoting risk<br />
factor management (see http://www.health.gov.au/<br />
internet/wcms/Publishing.nsf/C<strong>on</strong>tent/healthpubhlth-strateg-lifescripts-index.htm).<br />
7.1 BEHAVIOUR CHANGE GRADE LEVEL<br />
a) Every pers<strong>on</strong> with stroke should be assessed and in<str<strong>on</strong>g>for</str<strong>on</strong>g>med of <strong>the</strong>ir risk factors<br />
<str<strong>on</strong>g>for</str<strong>on</strong>g> a fur<strong>the</strong>r stroke and possible strategies to modify identified risk factors.<br />
The risk factors and interventi<strong>on</strong>s include:<br />
• smoking cessati<strong>on</strong>: nicotine replacement <strong>the</strong>rapy, bupropi<strong>on</strong> or nortriptyline A Level I<br />
<strong>the</strong>rapy, nicotine receptor partial ag<strong>on</strong>ist <strong>the</strong>rapy and/or behavioural <strong>the</strong>rapy<br />
359-361, 363-366<br />
should be c<strong>on</strong>sidered;<br />
• improving diet: a diet that is low in fat (especially saturated fat) and sodium, A Level I 367-369,<br />
but high in fruit and vegetables should be c<strong>on</strong>sumed;<br />
372, 376<br />
&II<br />
370, 373-375<br />
• increasing regular exercise; (meta-analysis of cohort studies in primary) C<br />
386-388<br />
preventi<strong>on</strong> dem<strong>on</strong>strate str<strong>on</strong>g link between low exercise and stroke risk<br />
• avoiding excessive alcohol. (meta-analysis of cohort studies in primary) C<br />
392<br />
preventi<strong>on</strong> dem<strong>on</strong>strate link between high alcohol intake and stroke risk<br />
b) Interventi<strong>on</strong>s should be individualised and may be delivered using behavioural A Level I 362-366,<br />
techniques (such as educati<strong>on</strong>al or motivati<strong>on</strong>al counselling).<br />
395, 396<br />
7.2 Blood pressure lowering<br />
High blood pressure is <strong>the</strong> major risk factor <str<strong>on</strong>g>for</str<strong>on</strong>g> both<br />
first and subsequent stroke. In general effective blood<br />
pressure management requires that blood pressure is<br />
maintained below acceptable limits (i.e. lower than<br />
140/90 mm Hg). 397 However, reducti<strong>on</strong> in blood<br />
pressure, irrespective of initial blood pressure, has<br />
been shown to reduce <strong>the</strong> recurrence of stroke and<br />
combined vascular events including myocardial<br />
infarcti<strong>on</strong>. 398 Reducing blood pressure is particularly<br />
important <str<strong>on</strong>g>for</str<strong>on</strong>g> patients who have diabetes where levels<br />
should be below 130/85 mm Hg. 397 Currently <strong>the</strong> most<br />
direct evidence available in sec<strong>on</strong>dary stroke<br />
preventi<strong>on</strong> is <str<strong>on</strong>g>for</str<strong>on</strong>g> <strong>the</strong> use of an ACE inhibitor or <str<strong>on</strong>g>for</str<strong>on</strong>g><br />
combinati<strong>on</strong> <strong>the</strong>rapy with an ACE inhibitor and a<br />
44