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CPG for Psychosocial Interventions in Severe Mental ... - GuíaSalud

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The highest evidence level found was selected <strong>for</strong> each <strong>in</strong>tervention questions. When there<br />

was a systematic review (SR) or meta-analysis <strong>in</strong> relation to the question, these were used as a<br />

source of evidence and the less solid and worst quality studies were rejected. When SR or metaanalyses<br />

could not be found, observational studies or case series were used.<br />

The evidence level of the <strong>in</strong><strong>for</strong>mation obta<strong>in</strong>ed from other sources, such as the a<strong>for</strong>ementioned<br />

<strong>CPG</strong>s, was ma<strong>in</strong>ta<strong>in</strong>ed, so long as the orig<strong>in</strong>al source that the evidence came from was<br />

clearly specified. In those cases where this was not clear, that <strong>in</strong><strong>for</strong>mation was used, but the evidence<br />

level was lowered to a lower level, and subsequently, the degree of recommendation.<br />

3.4. Form<strong>in</strong>g guidel<strong>in</strong>e recommendations<br />

Follow<strong>in</strong>g the critical appraisal of the available evidence, the recommendations were <strong>for</strong>mulated.<br />

A discussion group was made up with the entire <strong>CPG</strong> development group, us<strong>in</strong>g a well-reasoned<br />

op<strong>in</strong>ion, and bear<strong>in</strong>g <strong>in</strong> m<strong>in</strong>d the quality of the evidence found and the cl<strong>in</strong>ical experience of the<br />

<strong>CPG</strong> development group, the recommendations were gradually developed with their relative classification.<br />

Several recommendations were prepared <strong>for</strong> each answer, <strong>in</strong>dicat<strong>in</strong>g the level of evidence<br />

and degree of recommendation. When the recommendations were controversial or there was no<br />

evidence, it was solved by consensus of the development group. In those questions with respect<br />

to which there was no clear evidence about a particular topic, the group proposed research recommendations.<br />

3.5. Collaboration and external review<br />

The guidel<strong>in</strong>es established <strong>in</strong> the Methodology Manual <strong>for</strong> the Preparation of Cl<strong>in</strong>ical Practice<br />

Guidel<strong>in</strong>es <strong>in</strong> the (Spanish) National Health System 5 <strong>in</strong>clude the participation of expert collaborators<br />

and external reviewers. The expert collaborators participated <strong>in</strong> the review of the questions<br />

and the recommendations of the <strong>CPG</strong>s and the external reviewers contributed to the review of the<br />

draft. Be<strong>for</strong>e send<strong>in</strong>g the draft <strong>CPG</strong>s to the external reviewers, the cl<strong>in</strong>ical leaders of the <strong>CPG</strong> also<br />

carried out a review of the text. The guidel<strong>in</strong>e development group meticulously took <strong>in</strong>to consideration<br />

all the comments and contributions made dur<strong>in</strong>g the consultation period with the <strong>CPG</strong><br />

collaborators and reviewers and <strong>in</strong>troduced any changes they deemed appropriate derived from<br />

their comments. The recommendations made <strong>in</strong> this <strong>CPG</strong> do not necessarily have to co<strong>in</strong>cide or<br />

be <strong>in</strong> agreement with the contributions of the reviewers and collaborators. The f<strong>in</strong>al responsibility<br />

<strong>for</strong> the recommendations lies <strong>in</strong> the <strong>CPG</strong> development group.<br />

The <strong>in</strong><strong>for</strong>mative document <strong>for</strong> people with SMI and their families, prepared by the <strong>CPG</strong><br />

development group, was anonymously reviewed by people who suffer from SMI and their family<br />

members, <strong>in</strong>troduc<strong>in</strong>g appropriate changes as a result of their comments.<br />

The follow<strong>in</strong>g scientific associations collaborated <strong>in</strong> the preparation of this <strong>CPG</strong>: Aragonese<br />

<strong>Mental</strong> Health Association-Spanish Neuropsychiatry Association, National <strong>Mental</strong> Health Nurs<strong>in</strong>g<br />

Association, Spanish Psychiatry Society, Aragonese <strong>Psychosocial</strong> Rehabilitation Association,<br />

FL Crítica Versión 1.0.7 OSTEBA. Health Technologies Assessment Service Department of Health Basque Government http://<br />

www.euskadi.net/r33-2288/es/contenidos/<strong>in</strong><strong>for</strong>macion/metodos_<strong>for</strong>macion/es_1207/met<strong>for</strong>.html<br />

28 CLINICAL PRACTICE GUIDELINES IN THE SPANISH NHS

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