Model Organisms in Drug Discovery

more direct modeling of human diseases, demonstrating more extensively the
utility of Drosophila for MOA studies, genetic screens against phenotypes
generated by drug treatment and compound screens. Further technological
development is also necessary, especially in the areas of high-throughput
biology. However, the utility of Drosophila in drug discovery is now firmly
established and what remains to be determined is how much more this
remarkably robust model system can provide for the drug discovery process.
4.4 Acknowledgments
We would like to thank R. Fernandez and M. Konsolaki for critical review of
the manuscript and Q. Wang and X. Shi for technical help in establishing
automated fly sorting and dispensing methods.
4.5 References
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