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UNIVERSIDADE TÉCNICA DE LISBOA INS
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Fernandes, F., Loura, L. M. S., Fed
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Ao Pedro e Hugo, amigos de longa da
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2.2. - Peptides as models 2.3. - Am
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ABBREVIATIONS AND SYMBOL LIST ABBRE
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RESUMO RESUMO As biomembranas são
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SINOPSE SINOPSE Nas últimas duas d
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SINOPSE podem fornecer informação
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SINOPSE aceitantes. Dadores mais pr
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OUTLINE OUTLINE The last two decade
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OUTLINE membranes with a distributi
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OUTLINE BAR domains (tubulation of
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ion diffusion, as the energy requir
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acid. If no more groups are linked
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sphingomyelin, the most abundant sp
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signal for neighbouring cells to ph
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functional role in process such as
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in the L α phase, while lateral di
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1.7. Lateral heterogeneity in lipid
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the vesicle through bilayer deforma
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Figure I.9 - Depiction of the sever
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Figure I.11 - Experimentally obtain
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drying into a film and ressuspensio
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deactivating agents. Zwitterionic d
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amphipatic helices (see Section 2.3
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size corresponding to the hydrophob
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changes abruptly in the interfacial
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thickness of the bilayer (Section 1
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some α-helical membrane proteins a
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The formation of a lipid population
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homogeneous distribution of lipids
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Figure I.20 - Relative binding cons
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2.9. Lipid phase preferential parti
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- Page 83 and 84: 2430 Biophysical Journal Volume 85
- Page 85 and 86: 2432 Fernandes et al. Coat protein
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- Page 171 and 172: Abstract A group of proteins with c
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Methods Materials Peptides H0-NBAR,
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is the result of the immobilization
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where τ 0 is the lifetime of the d
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at very high concentrations, confir
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References 1. Farsad, K., and P. De
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TABLE I Membrane/Water partition co
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Fig. 7: H0-NBAR increases phospholi
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FIG. 2 18
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FIG.4 20
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Fig. 5B 22
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FIG.7A FIG. 7B 24
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CLUSTERING OF PI(4,5)P 2 IN FLUID P
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CLUSTERING OF PI(4,5)P 2 IN FLUID P
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CLUSTERING OF PI(4,5)P 2 IN FLUID P
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Absence of clustering of phosphatid
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where I is the fluorescence intensi
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certainly feasible that PI(4,5)P 2
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the tilt angle, and maintain a larg
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Chapter III ‐ Binding of Inhibito
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Chapter V - Interaction of Helix‐
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188
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Some of the biological questions de
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Bowman, E. J., Graham, L. A., Steve
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Farsad, K., Ringstad, N., Takei, K.
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Hinderliter, A., Biltonen, R. L., a
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Lodish, H., Berk, A., Zipursky, S.
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Nikura, K., Takeshita, N., and Taka
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Rodan, G. A. and Martin, T. J. (200
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J. Biol. Chem. 270: 17934-17938. Te