1 Selective serotonin reuptake inhibitors (SSRI) â sales, withdrawal ...
1 Selective serotonin reuptake inhibitors (SSRI) â sales, withdrawal ...
1 Selective serotonin reuptake inhibitors (SSRI) â sales, withdrawal ...
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2000 Medicines Control Agency, Committee<br />
on Safety of Medicines (2000). Current<br />
problems in pharmacovigilance,<br />
quantity. For the<br />
majority of the<br />
compounds the<br />
studies were not<br />
designed to study<br />
<strong>withdrawal</strong><br />
phenomena and lack<br />
sufficient<br />
observations in the<br />
critical period after<br />
stopping<br />
administration.<br />
In 1993 we alerted<br />
prescribers to the<br />
possibility of<br />
<strong>withdrawal</strong><br />
reactions occurring<br />
with paroxetine.<br />
Whilst the<br />
<strong>withdrawal</strong><br />
symptoms reported<br />
were generally not<br />
serious, there have<br />
been isolated<br />
reports of more<br />
serious symptoms<br />
on <strong>withdrawal</strong> such<br />
as severe electric<br />
shock sensations,<br />
vertigo and manic<br />
reactions.<br />
2000 EMEA CPMP 2278/00 Some of the <strong>SSRI</strong>s<br />
have been shown to<br />
reduce intake of<br />
addictive substances<br />
like cocaine and<br />
ethanol. The<br />
interpretation of this<br />
aspect is difficult.<br />
2002 Tonks A. (2002). Withdrawal<br />
from paroxetine can be severe,<br />
warns FDA.<br />
British Medical Journal, 324, 260.<br />
2002 MHRA response to Panorama<br />
programme on Seroxat<br />
FDA Warning<br />
against paroxetine<br />
because of the risk<br />
of <strong>withdrawal</strong><br />
symptoms.<br />
All <strong>SSRI</strong>s may be<br />
associated with<br />
<strong>withdrawal</strong><br />
reactions on<br />
Article in the<br />
bulletin sent out<br />
from the MCA<br />
to doctors,<br />
pharmacists,<br />
dentists and<br />
coroners<br />
News in BMJ<br />
Safety message