1 Selective serotonin reuptake inhibitors (SSRI) – sales, withdrawal ...

2003 Meeting 16 September CSM and
Expert group on Safety of SSRIs
2003 Committee on Safety of Medicines
and Expert Group on Safety of SSRIs.
Minutes of the meeting held Tuesday 25
November 2003.
http://www.mhra.gov.uk/home/groups/plp/documents/committeedocument/con003487.pdf
2003 Interim report of the Committee on Safety
of Medicines´ Expert Working Group on
Selective Serotonin Reuptake Inhibitors
September 2003
2003 WHO Pharmaceutical Newsletter 2003; no 1.
Drugs of abuse: Problems of data collection,
definitions and liability assessment.
drugs for which
drug dependence
has ever been
reported to the
Uppsala Monitoring
Centre database.
The group Minutes
expressed concern
about the lack of
data on the longtern
effect of SSRIs
and recommended
that further research
on this area was
required.
Professor
Minutes
Drummond
explained that he
had considered to
what extent the
SSRIs meet the
ICD-10 and DSM-
IV definitions of
dependence and has
concluded that the
extent to which
SSRIs meet the
criteria is much less
than with other
typically
dependence
producing drugs.
Two areas of Report
continual concern
…. and withdrawal
reactions on
stopping SSRIs.
However, such a Newsletter
conclusion may
only be drawn after
a careful review of
the significant
number of “drug
dependence” reports
for SSRIs received
by the ADR
monitoring system
and, not on the basis