Fluid balance and electrolyte distribution in human body.
Fluid balance and electrolyte distribution in human body.
Fluid balance and electrolyte distribution in human body.
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Water <strong>balance</strong><br />
– Sources for 2500 ml<br />
- average daily<br />
<strong>in</strong>take<br />
• Metabolic Water<br />
• Preformed Water<br />
– Ingested Foods<br />
– Ingested Liquids<br />
– Balance achieved if<br />
daily output also =<br />
2500 ml<br />
• GI tract<br />
• Lungs<br />
• Sk<strong>in</strong><br />
– evaporation<br />
– perspiration<br />
• Kidneys<br />
Water Movement Between the ICF <strong>and</strong> ECF<br />
Osmolality – the concentrations of solutes <strong>in</strong> water<br />
– solutes will <strong>in</strong>fluence the movement of water across membranes<br />
H 2<br />
O<br />
π = iRTc<br />
Aquapor<strong>in</strong>s- water channel prote<strong>in</strong>s <strong>in</strong> membranes<br />
Net filtration (Starl<strong>in</strong>g hypothesis)<br />
= forces favor<strong>in</strong>g filtration – forces oppos<strong>in</strong>g filtration<br />
As fluid flows through capillary it looses water <strong>and</strong> create greater osmotic<br />
return of water as it flows toward ve<strong>in</strong>ule end of capillary<br />
Forces favor<strong>in</strong>g filtration<br />
- Capillary hydrostatic pressure (blood pressure)<br />
- Interstitial oncotic pressure (water-pull<strong>in</strong>g)<br />
Forces favor<strong>in</strong>g reabsorption<br />
- Plasma oncotic pressure (water-pull<strong>in</strong>g)<br />
- Interstitial hydrostatic pressure<br />
H 2<br />
O<br />
filtration<br />
H 2<br />
O<br />
reabsorption
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