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2109 RES 13 GNAQ/11 MUTANT DEPENDENT UVEAL MELANOMA - SENSITIVITY TO MEK AND PI3K INHIBITION Scott E. Woodman, Xiaoxing Yu, Jahan Khalili, Chandrani Chattopadhyay, Michelle Williams, Nancy Poindexter, Martine J. Jager, Elizabeth Grimm, Dan Gombos, Bita Esmaeli 149 RES 14 INACTIVATING MUTATIONS IN BAP1 IN METASTASIZ- ING CLASS 2 UVEAL MELANOMAS J. William Harbour, Michael D. Onken, Lori A. Worley, Anne M. Bowcock, Eli Roberson 1944 RES 15 A RECURRENT DELETION OF THE BAP1 LOCUS IN OCULAR MELANOMA Suresh C. Jhanwar, Yuqiang Fang, Lu Wang, Klaus Busam, David H. Abramson 1843 RES 16 BAP 1 MUTATION IN TWO FAMILIES WITH UVEAL MELANOMA Miguel A. Materin, Camila Simoes, Ruth Halaban, J. William Harbour 12.00-12.30 Keynote Lecture: Dr. Ruth Halaban INSIGHTS FROM SEQUENCING THE MELANOMA EXOME 12.30-14.00 LUNCH AFTERNOON 14.00-14.45 Panel discussion Uveal Melanoma (Moderator J.W. Harbour) 14.45-15.45 Papers (Moderator D. Abramson) 103 RES 17 IDENTIFICATION OF MOLECULAR SUBGROUPS OF RETINOBLASTOMA M. Parulekar, G. Kapatai, M.A. Brundler, A. Peet, M. Wilson, H. Jenkinson, C. McConville 1820 RES 18 A NEW DISEASE: RETINOBLASTOMA WITH NO DETECTABLE RB1 MUTATIONS DRIVEN BY MYCN AMPLIFICATION Brenda L. Gallie, D.E. Rushlow, S. Yee, J.Y. Kennett, P. Boutros, N.L. Prigoda-Lee, W. Halliday, S. Pajovic, C. Spencer, B.L. Thériault, H. Dimaras, A. Raizis, C. Houdayer, W.L. Lam, T. Corson, D. Lohmann RESEARCH DAY <strong>Program</strong> 16 39 RES 19 TARGETING THE P-53 PATHWAY IN RETINOBLAS- TOMA PRECLINICAL MODELS WITH SUBCONJUNC- TIVAL NUTLIN-3A Rachel C. Brennan, Sara Federico, Cori Bradley, Jiakun Zhang, Jacqueline Flores-Otero, Matthew Wilson, Clinton Stewart, Fangyi Zhu, Kip Guy, Michael A. Dyer 1656 RES 20 RB DEPLETION SELECTIVELY INDUCES PROLIFERATION OF CONE-PRECURSOR LIKE CELLS David Cobrinik, Xiaoliang L. Xu, Suresh C. Jhanwar, and David H. Abramson 615 RES 21 TRB2 AND SKP2 IN THE RETINOBLASTOMA PATHWAY Xiaoliang L. Xu, Renbing Jia, Nengyi Zhou, Xianqun Fan, David H. Abramson, David Cobrinik and Suresh C. Jhanwar 1515 RES 22 NESTED RT-PCR DETERMINATION OF GD2 SYNTHASE AS A MARKER FOR MINIMAL DISEASE IN RETINOBLASTOMA IN THE CEREBRO-SPINAL FLUID (CSF). Viviana Laurent, Claudia Sampor, Jorge Rossi, Mariano Gabri, Maria T.G. de Davila, Daniel Alonso, Guillermo Chantada 15.45-16.15 BREAK 16.15-17.00 Papers (moderators R. Hurwitz, G. Chantada) 1824 RES 23 SUPER-SELECTIVE INTRA-OPHTHALMIC ARTERY CHEMOTHERAPY: RETINAL ENDOTHELIAL TOXICITY IN PRE-CLINICAL MODELS Matthew W. Wilson, J. Scott Williams, John S. Jackson, Fan Wang, Clinton F. Stewart, Timothy D. Mandrell, Barrett G. Haik, Jena J. Steinle 2107 RES 24 EMBRYONIC RETINAL TUMORS IN TRANSGENIC MICE CONTAIN CD133+ TUMOR-INITIATING CELLS Richard L. Hurwitz , Lalita Wadhwa, Wesley Bond, Laszlo Perlaky, Paul Overbeek, Mary Y. Hurwitz, Patricia Chévez-Barrios 2333 RES 25 TREATMENT OF LHBETATAG RETINOBLASTOMA TUMORS WITH ANGIOGENIC AND GLYCOLYTIC INHIBITORS AVOIDS CHEMOTHERAPY Samuel K. Houston, Timothy G. Murray, Yolanda Pina, Christina Decatur
50 RES 26 USING THE GLYCOLYTIC INHIBITOR 2-FLUORODEOXY- D-GLUCOSE, A NOVEL APPROACH TO TARGET THE CHEMORESISTANT CELL POPULATION IN LHBETATAG RETINAL TUMORS Yolanda Piña, Christina L. Decatur, Samuel Houston, Timothy G. Murray, Ludimila Cavalcante, and Theodore Lampidis 2140 Res 27 MTOR TARGETING IN COMBINATION WITH CHEMOTHERAPY: UPSTREAM REGULATION OF ANAEROBIC GLYCOLYSIS TO TARGET THE CHEMORESISTANT CELL POPULATION IN RB Timothy G. Murray, Yolanda Piña, Christina L. Decatur, Samuel Houston, Ludimila Cavalcante, and Theodore Lampidis 17.00-17.30 Discussion (moderator B. Gallie) RESEARCH DAY <strong>Program</strong> 17
Page 1 and 2: XV th NH City Hotel and Tower Boliv
Page 3 and 4: List of Congress Meetings of the In
Page 5: Table of Contents Welcome address K
Page 8 and 9: Keynote Lectures Lymphoma of the oc
Page 10 and 11: The venue for the Biannual Meeting
Page 12 and 13: Buenos Aires Downtown MAP 12 Venue
Page 15: MORNING 8.30-10.10 Papers (Moderato
Page 19 and 20: 2226 RES 4 NOTCH SIGNALING PROMOTES
Page 21 and 22: a reduction in the number of living
Page 23 and 24: array further detected copy number
Page 25 and 26: 615 RES 21 TRB2 AND SKP2 IN THE RET
Page 27: following treatment with 2-fluorode
Page 30 and 31: 1909 Rb14 RESULTS OF PATIENTS WITH
Page 32 and 33: Posters Retinoblastoma 2006 RBp100
Page 34 and 35: 120 RBp135 MANAGEMENT OF AN ECTOPIC
Page 36 and 37: After treatment, 10 patients lived
Page 38 and 39: Methods. Six cycles of carboplatin
Page 40 and 41: 1940 RB15 PROTON THERAPY FOR RECURR
Page 42 and 43: 4. Fluoroscopy for cannula placemen
Page 44 and 45: Methods. A retrospective chart revi
Page 46 and 47: Ruth A. Kleinerman1, Chu-ling Yu1,
Page 48 and 49: 2006 RBp100 RETINOBLASTOMA ASSESSME
Page 50 and 51: months. Mean delay between beginnin
Page 52 and 53: not associated with severity of RB.
Page 54 and 55: Conclusions. During a ten-year peri
Page 56 and 57: 30 RBp127 TREATMENT MODULATION IN R
Page 58 and 59: (follow-up 5 years). Two years afte
Page 61 and 62: 8.30-9.00 Poster presentations ECOp
Page 63 and 64: Uvea (Moderators: B. Damato, M. Sag
Page 65 and 66: Morning 8.30-9.00 Poster presentati
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1621 EC1 EVALUATION OF THE “HEDGE
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Purpose. Ocular surface squamous ne
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(cargusale@yahoo.com) Oncology Serv
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of the tissues most commonly affect
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2128 RF1 RETINOBLASTOMA David H. Ab
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Ocular Oncology Service, St Barthol
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Arturo Irarrazaval, Pablo Cazon, Os
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A CASE OF TEARING AND SWELLING OF T
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1849 ECp101 FIVE CASES OF CARCINOMA
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patients. The isolated involvement
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exudative fluid from the hemangioma
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maximum of 7 rituximab injections.
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153 UM14 PHENO-GENOTYPIC IDENTIFICA
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8.30-9.00 Poster presentations UMp1
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2253 UM1 PRELIMINARY STUDY OF VASCU
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Purpose. To determine the presence
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gene expression profile of melanocy
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the rarity of UM, timely completion
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C. Metz, T. Gkika, W. Sauerwein, N.
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Patients in the triamcinolone group
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1350 Ump101 INDUCED EXPRESSION OF P
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Purpose. To report the Results of R
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1547 Ump113 LONG-TERM OBSERVATIONS
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2038 Ump119 VALUE OF DOPPLER ANALYS
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Methods. A total of 4070 patients w
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First authors Naseripour, Masood No
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