Design of Simulated Moving Bed Chromatography - CPAC
Design of Simulated Moving Bed Chromatography - CPAC
Design of Simulated Moving Bed Chromatography - CPAC
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Conc.<br />
Standing Wave <strong>Design</strong>: Binary, Ideal, Linear Systems<br />
Desorbent<br />
Feed<br />
I II III IV<br />
Extract<br />
<strong>Bed</strong> Position<br />
Raffinate<br />
=<br />
= u<br />
= u<br />
= u<br />
F<br />
u<br />
Feed<br />
I<br />
w,slow<br />
II<br />
w,fast<br />
III<br />
w,slow<br />
IV<br />
w,fast<br />
=<br />
Sε<br />
b<br />
<br />
u<br />
III<br />
0<br />
u<br />
II<br />
0<br />
<br />
u w,i<br />
a<br />
= u 0<br />
a<br />
/ ( 1 + Pd i )<br />
= wave velocity <strong>of</strong> component i in zone a<br />
= L c / t s = port movement velocity<br />
F feed = feed flow rate<br />
u 0<br />
a<br />
= interstitial velocity in zone a<br />
e b = inter-particle void fraction<br />
P = (1 – e b ) / e b = bed phase ratio<br />
d i = distribution coefficient <strong>of</strong> i<br />
S = column cross-sectional area
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