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Chapter 4. Step One, Part One Cytokine Balance Inflammatory Pathway RNA Stress RNA Advanced Joint Inflammatory Pathway Support RNA A decrease in GABA levels on this neurotransmitter seesaw can cause a range of symptoms. In particular, GABA is a key to speech. (That’s why GABA is often used to help restore speech in stroke sufferers.) As a result, the return of language is often an outcome of balancing the glutamate/GABA seesaw. How does this work GABA is used by the brain to support sensory integration, helping us to tune in to the sounds we hear. With adequate GABA levels, we are able to dampen background sounds, so that it’s easier to distinguish the onset of a particular sound or word, which is how we recognize words and develop speech. With lowered GABA levels, spoken words sound like a long run-on sentence, rendering comprehension difficult. I always imagine that this is what these children hear until they get sufficient levels of GABA. In fact, often when they first recover language, their first communications will sound like a run-on sentence. That’s why children will understand better when parents speak slowly,with gaps between the words. Decreased GABA levels also increase anxiety, something that many of the children, their parents, and even the practitioners working with them tend to experience. Dealing with autism creates tremendous stress. Low GABA levels can also increase aggressive behavior, as well as decrease social behavior. Low GABA leads to decreased eye contact and difficulties in focusing. With some children, due to low levels of GABA, both eyes focus inward toward the nose, while other children may experience horizontal or vertical wavering of the eyes. Low GABA levels lead to decreased bowel function. It may seem counterintuitive that a calming neurotransmitter helps stimulate bowel activity, but GABA does indeed help the bowel to contract. In addition, GABA release may help to reduce the triggering of transient lower esophageal relaxations, decreasing gastroesophageal reflux (GERD). GABA is essential for proper intestinal motility. That’s why along with controlling glutamate, to help to create balance, many find it helpful to supplement directly with GABA as well as other natural substances such as valerian root, which indirectly helps to support GABA levels. In looking over the recommendations of useful supplements for GABA/glutamate balance, please note that in a few instances, I’ve noted how the supplements can be further fine tuned once you have your test results. If you don’t yet have your results, please use the supplements recommended for everyone. Autism: Pathways to Recovery 95
Maintaining a Healthy Glutamate/GABA Balance Branched chain amino acids (use only products that contain leucine/ileucine/ valine—but discontinue immediately if urine smells like maple syrup) Pycnogenol Grape seed extract GABA Nerve Calm Inflammatory Pathway Support RNA Lithium orotate (depending on levels on urine essential elements test) Sublingual GABA/ glycine Trehalose Valerian root Zen In addition, after you’ve gotten your test results, you can revisit the following additional supports in balancing GABA and glutamate, which build upon knowing your mutations. Progesterone cream (Best for ACE+/ MAOA+) Sublingual methylcobalamin (B12)—Only use following Nutrigenomic testing if recommended Sublingual cyanocobalamine—Useful for all unless contraindicated by test results Sublingual hydroxycobalamin—Useful for all unless contraindicated by test results Hydroxy B12 Oral Spray—Useful for all unless contraindicated by test results Liposomal B12 Taurine (depending on urine AA test levels—not for CBS + or SUOX + -) Theanine (Best for COMT V158M --) 96 Autism: Pathways to Recovery
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Autism: Pathways to Recovery NRI Ne
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Copyright © 2004, 2007, 2009 Neuro
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In loving memory of my parents.
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Chapter 2. Nutrigenomics and the Me
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CONCLUSION ........................
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Methylation Cycle Overview ........
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Suggested Protocol to Support Nerve
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exact phrases I might have chosen.
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Chapter 1. Discovering the Pathways
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Chapter 1. Discovering The Pathways
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support B12 in the body. I like to
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Tracking Detoxification What levels
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can harbor aluminum, which inhibits
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If you have been supporting to bypa
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acetic acid (5HIAA). Obsessive comp
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ily, histamine reactions, such as t
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II were correlated with increased a
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Strengthening All Parts of the Cycl
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with aluminum excretion from the bo
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Curcumin helps shift the emphasis t
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the methylation cycle function is s
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Chapter 7. Step Two, Part Two Incre
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Chapter 7. Step Two, Part Two For d
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Chapter 7. Step Two, Part Two Bacte
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Chapter 7. Step Two, Part Two As yo
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Chapter 7. Step Two, Part Two detox
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Chapter 7. Step Two, Part Two Metal
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Chapter 7. Step Two, Part Two detec
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Chapter 7. Step Two, Part Two in re
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Chapter 7. Step Two, Part Two a che
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Chapter 7. Step Two, Part Two Ammon
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Chapter 7. Step Two, Part Two also
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Chapter 8. Step Three Remyelinating
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Chapter 8. Step 3 Remyelinating of
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months, he was so obsessed with num
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increase in language would resolve
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contracted encephalitis when she wa
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Alivia recovered in a way that I ha
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Mit’s Story My precious Mit came
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experience of professionals placing
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he is at that moment of his life. I
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ecause it triggers detox/illness fo
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for the first time in nine years I
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Appendix: Flow Chart for Microbes F
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Appendix: Flow Chart for Microbes 2
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Appendix: Flow Chart for Microbes 2
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