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Supplementing with nucleotides, which are a form of our DNA bases, can help<br />

to both support thymidine, while maintaining appropriate methylation cycle activity.<br />

In addition, both iron and a form of folate called “5 formyl THF ” help<br />

to regulate SHMT activity. That’s why using lactoferrin (which helps to control<br />

iron levels) along with low doses of 5 formyl THF (found in the product, Acti-<br />

Folate) help shift methylation activity back to the short and long routes around<br />

the cycle.<br />

Understanding ACAT Mutations<br />

ACAT, (Acetyl-Coenzyme A acetyltransferase) impacts critical pathways and<br />

hence functional areas of human biochemistry in several ways, including:<br />

• Helping to form cholesterol<br />

• Assuring lipid balance and fluidity in the cell membranes, which in turns<br />

impacts neurological function<br />

128 Autism: Pathways to Recovery

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