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intake of P5P. I’ve noted that in certain instances, the use of high dose B6 or
P5P is not always helpful, and may cause overstimulatory or OCD type behaviors.
While kynurenic acid is a calming neurotransmitter, it’s converted by B6 or
P5P into quinolinic acid, which is an excitotoxin that can aggravate the nervous
system. Increased levels of quinolinic acid have been implicated in Alzheimer’s
disease and in excitotoxic damage of nerves. Quinolinic acid was found to be
substantially elevated in patients with Borrelia burgdorferi (Lyme) infection and
has been postulated that it contributes to the neurological and cognitive defects
associated with Lyme disease.
The Clean-Up
Again, it is normal to see symptoms during detoxification. At any point that you
are concerned about behaviors or physical symptoms, simply stop the program
and those symptoms will subside in several days. You can then start again later.
Some parents have used a combination of detoxification supports as a final “clean
up.” This combination includes the use of Metals I, Metals IV, and Microbial
Support RNAs along with Valtrex. Gradually increase the amount of the Metals
I and IV and Microbial Support over time in a manner similar to that described
above. Remember that this combination approach is only used after each of the
Metals RNAs has first been used individually.
Again, detoxification should always be conducted in conjunction with your
health care provider.
Visual Inspection
Although it is always gratifying to see progress, weekly urine tests can get expensive.
If you’re on a budget, watch the urine itself, and observe when it gets
dark and then light again. Send in the clear samples to get a measure of the metal
excretion. This will be easier on the pocketbook, However, remember that this
will not monitor creatinine and potential viral excretion, and you may miss some
metals. A number of parents have also taken advantage of creatinine test strips.
These will not give you a quantitative measure of creatinine but they will give
you a sense of the trend, and whether it is increasing or decreasing, and you can
use them in conjunction with biweekly, or every third week, spot urine tests. Another
reason not to rely solely on the creatinine test strips is that, unlike mercury
or lead, aluminum excretion appears to be independent of the creatinine levels.
Sending in spot urine samples should be done on a regular basis, even if the
creatinine numbers have not dropped. In addition, testing for essential minerals
(UEE) along with the toxic metal excretion is very important. As I have mentioned,
essential minerals can be excreted along with toxic metals, and mineral
depletion can be a cause for concern. For this reason alone, you should perform
occasional spot urine tests regardless of the creatinine number and also include
184 Autism: Pathways to Recovery