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Common Mental Disorders Depression - New Zealand Doctor

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Chapter 6 Management of depression in adults/pakeke<br />

Atypical depression<br />

Atypical depression generally presents with symptoms such as over-eating and oversleeping.<br />

The patient may report that their mood improves in response to positive<br />

events, and the mood disorder may be preceded by a longstanding sensitivity<br />

to rejection. 243 Compared to other patients with depression, those with atypical<br />

depression are more commonly female, with younger age of onset and a more severe<br />

degree of psychomotor retardation, which can be described as ‘leaden paralysis’. 65<br />

Treatment with an SSRI is appropriate. If the patient does not respond to an SSRI and<br />

has significant functional impairment, they should be referred urgently to secondary<br />

care mental health services for consideration of other strategies. 65<br />

6.2 Prevention of relapse or recurrence<br />

Ongoing strategies are needed to reduce the risk of relapse or recurrence of<br />

depression. Many patients do not receive adequate follow-up after treatment and do<br />

not persist with ongoing preventive measures, 338 partly because primary care models<br />

tend to emphasise acute care and rely on patient-initiated follow-up.<br />

Chronic disease management models have shown the effectiveness of relatively simple<br />

interventions, such as ensuring regular follow-up during treatment, proactive ongoing<br />

telephone follow-up of patients at risk, support for self-management, and relapseprevention<br />

planning after recovery from an acute episode. 142<br />

Adults/pakeke taking antidepressants should normally continue to take them for at<br />

least 6 months after remission of a first episode of depression as this greatly reduces<br />

the risk of relapse. 354 After a second or subsequent episode, antidepressants should<br />

be continued for at least 2 years. 9 Maintenance therapy needs to address not only the<br />

issue of how long the person should continue taking antidepressants but also what other<br />

nonpharmacological strategies are necessary for this individual. 277 Various psychological<br />

therapies (such as CBT, behavioural therapy [BT], interpersonal psychotherapy<br />

[IPT] and mindfulness-based cognitive therapy) either alone or in combination with<br />

antidepressants, have been shown to reduce the long-term risk of relapse. 334,335,355-357<br />

The relevant studies delivered therapy in a variety of formats, ranging from 8 sessions<br />

weekly, 335,355 to 16 sessions over 20 weeks plus ongoing booster sessions. 357<br />

Once the patient has recovered from an acute episode and before he/she is<br />

discharged, the practitioner should discuss with the patient the need to be vigilant for<br />

early indications of relapse. 358 The patient should be strongly encouraged to continue<br />

with preventive measures, such as maintaining lifestyle changes and complying with<br />

maintenance therapies. Early warning signs and triggers of possible recurrence should<br />

be discussed and the patient should have planned in advance what steps to take,<br />

if necessary. 142 Appendix F: Self-management Resources includes a web address for<br />

Identification of <strong>Common</strong> <strong>Mental</strong> <strong>Disorders</strong> and Management of <strong>Depression</strong> in Primary Care 79

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