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Common Mental Disorders Depression - New Zealand Doctor

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psychological therapies were of equivalent efficacy to other treatments (in most cases<br />

antidepressants and GP care), but were better tolerated.<br />

A recent <strong>New</strong> <strong>Zealand</strong> study 388 compared CBT and IPT in 177 outpatients with<br />

depression and found CBT and IPT equally effective for mild and moderate<br />

depression, with about 55% of patients experiencing at least a 60% reduction in<br />

symptom scores over 16 weeks. Cognitive behavioural therapy was more effective than<br />

IPT in severe depression. Melancholia did not predict poor response to either therapy.<br />

Other evidence from mixed settings suggests that CBT, IPT and BT are as effective as<br />

antidepressants 65,331-333 and that CBT and BT may have a longer-lasting effect. 65,389<br />

Both IPT and CBT may be useful as a maintenance treatment. 65 Combined therapy<br />

with CBT and antidepressants may enhance the effectiveness and tolerability<br />

of treatment, particularly for people with more severe depression 65 and may also<br />

reduce relapse rates in patients with residual symptoms. 65<br />

A 2006 meta-regression of studies from a variety of settings found that the mode<br />

of delivery of CBT did not impact on its effectiveness, although the evidence for<br />

telephone and computerised CBT was limited. 390 It was unclear to what extent the<br />

professional background of the therapist affected efficacy: it was clear that trained<br />

psychologists delivered effective therapy, but there was insufficient evidence to<br />

determine the effect of delivery by other health care practitioners. 390<br />

Psychological therapies: issues for evidence-based practice<br />

The evidence on psychological therapies applies to ‘textbook’ approaches which target<br />

depression and have a behavioural element, such as CBT, BT, IPT, MBCT and PST.<br />

The GDT notes that in practice most therapists use a less structured approach than the<br />

methods used in research and it is unclear whether this influences clinical outcomes.<br />

Given the resource problems with formal therapy, it may be useful for members of<br />

primary care teams to develop the skills to teach simple cognitive strategies such<br />

as PST, activity scheduling and goal-directed therapy. Ideally, these therapies will<br />

be provided within primary care, 352 but some skills may need to be introduced from<br />

elsewhere. Any psychological therapy offered in the treatment of depression should<br />

use a recognised therapeutic approach (eg, CBT, IPT or PST) which focuses on<br />

depression, resilience and behavioural support, or includes components targeted to<br />

the individual’s specific problem. 9,65<br />

Other features likely to affect outcomes but which have not been subject to controlled<br />

comparison are a good therapeutic relationship and (on the part of the patient)<br />

motivation, positive expectations and receptiveness to the therapeutic model. 391<br />

The NICE (2004) findings on non-specific counselling derive from three studies of<br />

widely differing and eclectic approaches and need to be viewed with caution. In the<br />

opinion of the GDT, psychological therapies that encourage rumination may not be<br />

helpful for people with depression and may potentially cause harm. Currently, there<br />

is a trend towards the use of specific interventions such as behavioural activation, a<br />

type of behavioural therapy that is a component of CBT. In the opinion of the GDT,<br />

84<br />

Identification of <strong>Common</strong> <strong>Mental</strong> <strong>Disorders</strong> and Management of <strong>Depression</strong> in Primary Care

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