Program - Association for Chemoreception Sciences

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9:15 am #7 Novel proteolyzed ENaC isoforms and corresponding salttaste enhancing compoundsKambiz Shekdar, Jessica Langer, Purvi Shah, Joseph Gunnet,Dennis Sawchuk. Chromocell Corporation, North Brunswick,NJ, United States9:30 am #8 Recovery from Potassium Chloride (KCl) Loading AltersAmiloride-Sensitive Salt Taste in HumansGeorge M Feldman 1,2 , Gerard L Heck 2 , Nancy L Smith 1 .1Dept of Veterans Affairs, Richmond, VA, United States,2Virginia Commonwealth University, Richmond, VA,United States9:45 am #9 Comparative Analysis of Bitter Taste Receptor AgonistActivationMaik Behrens 1 , Stephan Born 1 , Anne Brockhoff 1 , Masha Y.Niv 2 , Wolfgang Meyerhof 1 . 1 German Institute of HumanNutrition Potsdam-Rehbruecke, Dept. Molecular Genetics,Nuthetal, Germany, 2 The Hebrew University of Jerusalem,Institute of Biochemistry, Food Science and Nutrition,Faculty of Agriculture, Food and Environment, Rehovot, Israel10:00 am – 10:30 am BREAKBanyan Breezeway16 | AChemS Program 2010
10:30 am – 12:35 pm SYMPOSIUM – GENETICS OF HUMAN OLFACTIONExclusively sponsored byChair/Organizer: Danielle ReedIsland BallroomThe contribution of genetic effects to human olfactoryperception in humans is largely unknown. Genetic modelingstudies using twins suggest both genetic and environmentaleffects influence olfactory perception but the research isrelatively sparse and does not fully take into account the widediversity of odorants and the possibility that the geneticarchitecture of odor perception may differ by odorant typeor other features of the stimulus. Data do, however, supportthe notion that individual differences in olfaction areheritable and studies of genotype-phenotype relationshipshave begun. Genetic variation in odorant receptors is a logicalfirst choice to examine for alleles that affect perception. Thusolfactory receptor segregating pseudogenes, cSNPs and SNPsin regulatory regions, copy number variants and otherchromosomal structural variants are candidates that mayunderlie individual differences in olfactory sensitivity. In thissymposium the nature of these differences in humanolfactory perceptions and their associations with underlyinggenotypes will be explored.T H U R S D AY10:30 am #10 Environmental and Genetic Effects on HumanOdor PerceptionMarkus Perola 1 . 1 National Institute for Health and Welfare,Helsinki, Finland, 2 University of Helsinki & FIMM, Helsinki,Finland10:55 am #11 Phenotype/Genotype Associations in Human OlfactionCharles J. Wysocki 1 , Danielle R. Reed 1 , Doron Lancet 2 , YehuditHasin 2 , Antti Knaapila 1 , Jennifer Louie 1 , Fujiko Duke 1 , LisaOriolo 1 . 1 Monell Chemical Senses Center, Philadelphia, PA,United States, 2 Weizmann Institute of Science, Rehovot, Israel11:20 am #12 A genome-wide perspective on the perception ofmusk-like odorantsAntti Knaapila 1 , Gu Zhu 2 , Danielle R. Reed 1 , Charles J.Wysocki 1 , Hely Tuorila 3 , Markus Perola 4 , Nicholas G. Martin 2 ,Margaret J. Wright 2 . 1 Monell Chemical Senses Center,Philadelphia, PA, United States, 2 Queensland Institute ofMedical Research, Brisbane, Australia, 3 University of Helsinki,Helsinki, Finland, 4 National Institute for Health and Welfare,Helsinki, FinlandProgram in Detail | 17
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Program - Association for Chemoreception Sciences

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