14.45–15.00 [O4] Predicting outcomes in sporadic versus hereditary breast cancer: a limitedimmunohistochemical panel does not identify BRCA1 and BRCA2 carriers{P} DL Holliday, C Chelala, P Goinath, DM Eccles, JL Jones15.00–15.15 [O5] An altered myoepithelial cell phenotype in DCIS influences tumour-associatedangiogenesis{P} SJL Payne, M Allen, I Hart, JL Jones15.15–15.30 [O6] Genomic and immunophenotypical characterisation <strong>of</strong> pure micropapillarycarcinomas <strong>of</strong> the breast{P} C Marchio, M Iravani, R Natrajan, MB Lambros, K Savage, S Di Palma,FC Schmitt, G Bussolati, IO Ellis, A Ashworth, A Sapino, JS Reis-Filho15.30–16.10 TEA [SPORTS HALL 1]Detailed Programme – Tuesday 1 July <strong>2008</strong>Presenter = {P} · Abstract numbers are shown in bold and square brackets eg [S123]16.10–16.25 [O7] Neural networks identify gene pr<strong>of</strong>iles that predict clinical outcome with highaccuracy in breast cancer: CA IX is identified as the principal prognostic indicatorLJ Lancashire, {P} DG Powe, E Rakha, AR Green, R Mukta, EC Paish, RC Rees,IO Ellis, GR Ball16.25–16.40 [O8] Clear cells <strong>of</strong> the nipple epidermis: a reserve <strong>of</strong> motile mammary precursor cells?{P} J Going, M Currie16.40–16.55 [O9] Development and characterisation <strong>of</strong> a new breast cancer cell line <strong>of</strong> basalphenotype{P} V Speirs, CA Green, RH Partanen, AM Shaaban, AM Hanby14.00–17.00 Conference Auditorium 2ORAL COMMUNICATIONS: GastrointestinalChair: Dr MJ Arends, University <strong>of</strong> CambridgeDr N Scott, St James’s Institute <strong>of</strong> Oncology, <strong>Leeds</strong>14.00–14.15 [O10] Methylation pattern <strong>of</strong> high risk flat adenomas in CRC{P} QJM Voorham, B Carvalho, AJ Spiertz, NCT Van Grieken, S Derks,H Grabsch, B Rembacken, AP De Bruïne, M Van Engeland, GA Meijer14.15–14.30 [O11] Combining proteomics and genomics to identify biomarkers for colorectal cancer{P} M De Wit, CR Jimenez, B Carvalho, S Piersma, R Lamerichs, GA Meijer,RJA Fijneman14.30–14.45 [O12] Chromosomal aberrations and APC promoter methylation in sporadic and coeliacdisease related small intestinal adenocarcinomas{P} B Diosdado, TE Buffart, M Tijssen, BJ Bolijn, B Ylstra, B Carvalho,R Watkins, F Lewis, ID Nagtegaal, CJJ Mulder, K Maude, H Grabsch, P Quirke,P Howdle, GA Meijer14.45–15.00 [O13] K-Ras and B-Raf mutations in the MRC CR08 FOCUS Trial{P} S Richman, P Chambers, F Elliott, C Daly, M Braun, J Barrett, G Taylor,P Quirke, M Seymour, and MRC Focus Investigators15.00–15.15 [O14] Patient survival according to the quality <strong>of</strong> colonic cancer surgery: time for action?{P} NP West, EJA Morris, O Rotimi, A Cairns, PJ Finan, P Quirke12 <strong>Summer</strong> <strong>Meeting</strong> (194 th ) 1–4 July <strong>2008</strong> Scientific Programme
Detailed Programme – Tuesday 1 July <strong>2008</strong>Presenter = {P} · Abstract numbers are shown in bold and square brackets eg [S123]15.15–15.30 [O15] <strong>The</strong> prognosis <strong>of</strong> oesophageal carcinoma depends on the number <strong>of</strong> lymph nodesexamined in the resection specimen{P} CP Twine, WG Lewis, A Casbard, MA Morgan, D Chan, GWB Clark,T Havard, TD Crosby, SA Roberts, GT Williams15.30–16.10 TEA [SPORTS HALL 1]16.10–16.25 [O16] MAL is silenced by promoter hypermethylation in gastric cancerTE Buffart, RM Overmeer, RDM Steenbergen, M Tijssen, NCT Van Grieken,PJF Snijders, H Grabsch, CJH Van De Velde, {P} B Carvalho, GA Meijer16.25–16.40 [O17] Regulation <strong>of</strong> the adenomatous polyposis coli gene by the miR-135 family incolorectal cancer{P} B Diosdado, R Nagel, C Le Sage, M Van Der Waal, JAF Oude Vrielink,A Bolijn, GA Meijer, R Agami16.40–16.55 [O18] An interobserver study <strong>of</strong> mandard grading in patients receiving preoperativechemoradiotherapy for advanced rectal cancerI Craven, {P} N Scott, O Rotimi, C Verbeke, D Sebag-Montefiore17.00–18.00 Conference Auditorium 1PUBLIC LECTUREChair: Pr<strong>of</strong> DA Levison, President, <strong>Pathological</strong> <strong>Society</strong>MRSA/Hospital acquired infectionPr<strong>of</strong> PH Pennington, University <strong>of</strong> Aberdeen18.30–21.30 Parkinson Court, Parkinson Building, University <strong>of</strong> <strong>Leeds</strong>WELCOME RECEPTIONHosted by the Section <strong>of</strong> Pathology and Tumour Biology, <strong>Leeds</strong> Institute <strong>of</strong> MolecularMedicine, University <strong>of</strong> <strong>Leeds</strong>Sponsor: Leica Microsystems<strong>The</strong> Right Worshipful the Lord Mayor <strong>of</strong> <strong>Leeds</strong>, Councillor Frank Robinson, accompaniedby the Lady Mayoress, Mrs Sheila Robinson, will be attending.<strong>Summer</strong> <strong>Meeting</strong> (194 th ) 1–4 July <strong>2008</strong> Scientific Programme13