from first principles PP-I-1

PP-V-1Electrocatalytic Oxidation of Glycine at a Nano-Structured Ni ChelidamicAcid and Bimetallic Au-Pt Inorganic-Organic Hybrid Nanocomposite ontoGlassy Carbon Modified ElectrodeAbbasi A.R. 1 , Azadbakht A. 21 Department of Analytical Chemistry, Faculty of Chemistry, Razi University, Kermanshah, Iran2 Department of Chemistry, Faculty of Science, Khorramabad Branch,Islamic Azad University, Khorramabad, IranAbbasi.Amirreza@gmail.comAmino acids are essential building blocks of biological molecules and play key roles in manyneuro-chemical response mechanisms, such as memory, appetite control and paintransmission [1]. The disruption of amino acid regulation has been linked to many disorderssuch as Huntington, Alzheimer and Parkinson diseases [2]. In this research a novel nickelcomplex was used as electrocatalyst for electrooxidation of glycine. A nano-structured nickelcheliamic acid was electrodeposited on a bimetallic Au-Pt inorganic-organic hybridnanocomposite modified electrode. The electrode possesses a three-dimensional (3D) porousnetwork nanoarchitecture, in which the bimetallic Au-Pt NPs serving as metal nanoparticlebased microelectrode ensembles are distributed in the matrix of interlaced 3,3′,5,5′-tetramethylbenzidine (TMB) organic nanofibers (NFs). The hydrodynamic amperometry atrotating modified electrode at constant potential versus reference electrode was used fordetection of glycine. Under optimized conditions the calibration plots are linear in theconcentration range 1µM- 0.75mM and detection limit was found to be 0.3µM.References:[1] A.J.Meijer, P.F. Dubbelhuis, Biochem. Biophys. Res. Commun. 313(2004)3 97.[2] D.C. Javitt, Biol. Physchiatry, 67(2008) 6.310