Summary of HIR Equipment (2012-2013) - High Impact Research

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HIR-MOHE EQUIPMENT 2012 - 2013 (FACULTY OF SCIENCE)No PI's Name Project Title EquipmentEstimated budgetYear 2&3(2012-2013)2012(RM)Approved Budget(After VM Lab)2013(RM)Total(RM)Quantity/UnitOriginCountry ofDetails Justification of purchaseAdditional information(space/utilities eg electric, software etc)Potential users/research groups9 Prof Dr. Rauzah Hashim,- Assoc Prof Dr. ThorstenHeidelberg,- Rusnah Syahilah DualiHussen ,- Nasrul Zamani Mohd Rodzi ,- A. Sugimura (Osaka SangyoUni),- H. Naito (Osaka PerfectureUniversity),- Osama Abou Zeid (SultanQaboos University)10 Prof. Dr Edward R.T. Tiekink,Prof. Dr Ng Seik Weng, Assoc.Prof. Lo, KM, Dr N. Halim, DrTan Kong WaiHIR 11 - Understanding 1 Photon correlation250,000.00 250,000.00 - 250,000.00 1 UK determination of particle size and size distribution (range ~ 1 The determination of particles sizes and size distribution is an essential stand alone benchtop system with standard 2-phase electricGuerbet glycosides selfassemblystructures andparticle sized between 5 nm and 10 mmcritical for potential applications. The zeta-potential enables a prediction on space (~80 cm bench, < 30 kg) for placement in M008bspectroscopynm to 5 mm diameter); Zeta-potential measurements for feature in the formulation studies for vesicles, as these parameters are supply (80 W/220V) and no special room requirements; labdynamics for functionalthe stability for dispersions and emulsions and, therefore, is an important available; no special maintenance of equipment and nonano-biotechnologyfeature for formulation designs as well. The optimization of formulations updating of software or databases required; repairs requirerequires accessibility of the analytical instrument. Although an instrument authorized engineerwith required feaures is available in UM, the machine is heavily utilized andaccess is limited to one paticular day in the week.These restrictions preventan effective fromulation study and, thus, affect the progress of the research.250,000.00 250,000.00- 250,000.00HIR 12 - NanoCav 1 Modular spectophotometer 194,685.00 194,685.00 - 194,685.00 1 USA/Japan This attachment is designed to enable the measurement of There is no equipment in UM to perform this function. This equipment will At present UM does not have this capability. However, oncevariable temperature solid-state responses of particular interest allow efficient screening of synthetic compounds for their solid-state the instrument has been installed and is operational, it isto this gold but, also to the metal-organic framework project photoluminescence characteristics that can be correlated with their crystal hoped that chemists working in all chemistry disciplines will(HIR/SC/03). At present we obtain such data from collaborators structures. Our previous experience has shown that the addition of these avail themselves of this spectroscopic opportuntity. Ideally,from around the world but for high-throughput in-house data to our research projects enables publication in high-impact Journals this modular attachment can be added on to a pre-existinganalysis, effective and vital spectroscpic data may be collected such as CrystEngComm and Crystal Growth & Design. Other targetted highimpactJournals for our research output in Dalton Transactions, Chemistry of should be no special space requirements for the newspectrophotometer and removed, as necessary. Thus, therein a timely fashion.Materials, Journal of Materials Chemistry and Chemical Communications. equipment.In summary, a key component of both Tiekink's HIR3 and HIR12 projects isthe measurement of variable temperature solid-state luminescence data toenable higher-quality publications.194,685.00 194,685.00 -194,685.0011 Prof Dr. Kurunathan HIR 13 - Network Analysis 1 SGI Altix UV100-XE: HighRatnaveluof Social, TechnologicalPerformance Computerand Biological Networks(HPC) [Integrated Compute,Storage & GPGPUAccelerated System: 4 x 6-core Intel Xeon 2.66GHzprocessor, 32 x 2GB DDR3system memory, 4 x 3TB7200RPM SATA storage, 1 xNVIDIA M2090 Tesla GPU,1 x NVIDIA QUADRO 6000GPU]249,991.00 249,991.00 - 249,991.00 1 USA 1. Development of massively parallelized graph layoutalgorithms by utilizing a GPGPU (General Purpose GraphicsProcessing Unit) implementation of the Barnes-Hut n-bodysimulation algorithm.2. Development of GPGPU Monte Carlo algorithms for largenetwork dynamics (time evolution) simulations.Fast (large) network layout algorithms and Monte Carlo network evolution Requires constant air-conditioned environment and UPSsimulations scheduled for development under this project require hardware (Uninterrupted Power Supply) system. This system takes up a(GPGPU) acceleration using the CUDA (Compute Unified Devicesmall footprint (uses 3U chasis: D650 X W483 X 133H mm).Architecture) and OpenCL (Open Compute Language) framework. CUDA andOpenCL enable direct interface to the 512 compute cores on the NVIDIATesla M2090 GPU to deliver a peak performance of up to 600 gigaflops (600billion floating point operations per second) in double-precision. In contrast,a quad-core Xeon X5365 processor delivers only 38 billion flops (under theLINPACK benchmark). An equivalent GPU-accelerated SMP (SymmetricMultiprocessing) HPC is not available in UM.2 Other peripherals 40,000.00 25,000.00 15,000.00 40,000.00 1 Provisioned for procurement of additional 2 units of NVIDIATesla M2090 cards.289,991.00 274,991.00 15,000.00289,991.0012,121,526.00 10,334,676.00 1,605,800.00 11,940,476.00 Total 39To develop scalable multi-GPU (GPU-cluster) network layout/Monte Carlocodes.No additional hardware requirement - the Altix UV 100-XEcan host another two (2) GPUs. Codes developed for single-GPU runs will be modified to work on multiple GPUs.- updated on 2nd March 2012 -
HIR-MOHE EQUIPMENT 2012 - 2013 (FACULTY OF DENTISTRY)Approved Budget(After VM Lab)No PI's Name Project Title EquipmentEstimatedbudgetYear 2&3(2012-2013)Quantity/unitCountry oforiginDetailsJustification ofpurchaseAdditional information(space/utilities eg electric, softwareetc)Potential users/research groupsFrequency andintensity of usage2012(RM)2013(RM)Total(RM)1 Prof. Dr. Rosnah Mohd. Zain;Biobanking of oral cancers: An1 Enhancement of415,000 415,000 - 415,000 1 Malaysia The system to be procured is an 1) Limited capacity of the existing database: With theSpace available at the new post-Currently 3 HIR and 5 UMRG projectsFor database, usageCo-PI: Prof. Dr. Zainal Ariffassessment of survival,databaseentry level set-up which willexpanding data, we need to enhance our databasegraduate building, Fac of Dentistry.are using the data and specimen fromdepends on request fromAbdul Rahmanclinicopathological parameters,management strategies, nutrition andgenetic susceptibility of patientsconsist of servers for data and biobank system to cope with the huge amount of Workstation, hardware and softwarestorage and processing, highendworkstations, applicationdata collected over the years. Furthermore, in the included.future, we also plan to include and link all researchNeeds air-conditioned room for serverfindings such as genetic and 'omics' data.software, storage managementwhich is available.In2) No integration of softwares/ programs: Currently,solutions and databases that willthe future, it is planned that geneticthere are few programs/ softwares that was purchasedbe used as a platform to supportor developed in-house for data, specimen and image(transcriptome, 'omics') data fromand integrate existing standaloneapplication programs, efficient data and image retrieval.will be added to database.storage. These programs needs to be integrated for research findings (profiling, NGS etc)databases and low-end3) Lack of appropriate infrastructure: Currently, the Previously this database/biobank hashardware.The system will also oral cancer database is installed and kept on a low-been utilised by 8 projects (E-Science,the biobank/database. Another 2 HIR various projects/reseachers/projects pending approval from KPT is postgrads on weekly basis.also planned to utilise the resources For the specimen/biobank,from the biobank/database. Eventually usage almost on daily basis,the proposed enhancement of database either in terms of specimenwill enable all researchers including requests, process andpostgraduates, scientists from various storage.groups to extract relevant/requireddata/specimen. The credibility of thisdatabase/biobank system has beeninclude data recovery andend laptop and the data is backed up on CDs andUMRG, IRPA) where more than 35recognised where internationalbackup components. In addition, thumbdrives. We need a high-end and high capacitypapers has been published.collaborators has also utilised ourappropriate networking systemwill also be made available forefficient data entry and retrievalwithin a client/serverarchitecture.data storage facility (ie. servers) to house and securethe voluminous data. We also need appropriate serverto back up the valuable and critical data. As the dataincreases, we also need high end workstations so thathuge data and images can be uploaded and retreivedmore efficiently.data/specimen.2 Prof. Dr. Zainal Ariff AbdulConstructing the cancer progression1 License for20,000 - - 0 10,000/ per year Sweeden License for software for Systems This software is required for the analysis of theThis software will be installed in anThis software will be primarily used byThe software will be usedRahman ; Co-PI:Prof. Dr.model: The identification of key playerssoftware forBiology analysis (PathwayLab,different pathways involved in cancer progression. In existing computer and no additionalour team to analyse the cross talkextensively after theCheong Sok Chingin malignant transformationSystems BiologyInNetics Sweeden).particular, it will help with the analysis of crosstalkspace or utilities are neededbetween the epithelial cells and themicroarray experiments areanalysis(PathwayLab,InNeticsbetween epithelial compartment and the tumourmicroenvironment.tumour microenvironment. However, the completed. The software willsoftware will be useful for anybe used extansively againresearcher who is working on systems during the validation stageSweeden).biology.when we identify additionalpathways that could beperturb by specific genesthat control malignanttransformation.435,000 415,000 0 415,000 2Rejected after VM Lab- updated on 2nd March 2012 -
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