Summary of HIR Equipment (2012-2013) - High Impact Research

HIR-MOHE EQUIPMENT 2012 - 2013 (CHANCELLORY)Estimated budgetApproved Budget (After VM Lab)Quantity Country ofJustification ofAdditional informationNo PI's Name Title EquipmentYear 2 & 3Details/unitoriginpurchase(space/utilities eg electric, software etc)(2012 & 2013 )2012 (RM) 2013 (RM) Total (RM)7 Dr. Faisal Rafiq Mahamd Integrated Photonics for 1 Low temperature45,000 45,000 - 45,000 1 UK A pyrometer is essentially a type of temperature sensor. It Our fibre drawing tower is the only one in South East Asia at the No additional space required. This item is small and will beAdikanBiosensorspyrometerwill be fitted into our optical fibre drawing tower to output moment. Equiping the tower with such pyrometer will extend its fitted to our furnace.temperatures ranging from 200 degrees celcius up to 2100 capability to operate on soft glasses and novel materials - highdegrees celcius.impact.2 Optical spectrum70,000 70,000 - 70,000 1 US/Japan Optical spectrum analysers provides wavelength information. Optical spectrum analysers are common test and measurement Benchtop. No additional space or facilities required.analyserThe basis of sensing in our project focuses on wavelength equipment in any optical laboratory.(IR wavelengthdynamics.region)3 Optical spectrum60,000 60,000 - 60,000 1 US/Japan Optical spectrum analysers provides wavelength information. Optical spectrum analysers are common test and measurement Benchtop. No additional space or facilities required.analyserThe basis of sensing in our project focuses on wavelength equipment in any optical laboratory.(UV wavelengthdynamics.region)4 Tunable laser source 75,000 75,000 - 75,000 1 US/Europe/ A laser source is complementary to a spectrum analyser. The Similar to optical spectrum analysers, tunable sources are common Benchtop. No additional space or facilities required.Japan wavelength emitted by the laser source will be detected by in any optical laboratory.the spectrum analyser.5 Clean room, wet200,000 - - 0 1 Local A clean environment and a support facility that would allow NO LONGER REQUIRED.N/A.bench and facilitiessurface functionalisation of sensor chips.We will rely on a central facility and sister laboratories.We wish to reallocated the budget to purchase items related toglass processing.6 High temperature50,000 - - 0 1 Japan/ Europe A box furnace for glass melting and shaping. NO LONGER REQUIRED.N/A.silicon carbideWe will rely on a central facility and sister laboratories.furnaceWe wish to reallocated the budget to purchase items related toglass processing.7 Various optics and50,000 50,000 - 50,000 numerous Local/ Europe/ US These include lenses, mirrors, mounts, drills, tool sets. The Important sundry items for operation of tower and alsoSmall items. No additional space or facilities required.mechanical toolsitems will find use either in our characterisation lab or the characterisation set up.fibre tower.8 Scopes and power100,000 - 100,000 100,000 numerous Local/ Europe/ US The oscilloscopes and power meters provide time, frequency Important test and measurement items for characterisation of Benchtop. No additional space or facilities required.metersand power measurement capabilities.fabricated sensors.9 Laser sources 35,000 - 35,000 35,000 1 US/ Europe/ A laser source is complementary to a spectrum analyser. The Similar to optical spectrum analysers, these laser sources are Benchtop. No additional space or facilities required.Japan wavelength emitted by the laser source will be detected by common in any optical laboratory.the spectrum analyser.10 Optical benches 50,000 - 50,000 50,000 1 US/ Europe/ A vibration insensitive bench, with necessary accessories. We anticipate that the laboratory will expand, and therefore the Typically measuring 1m by 2.5m. A room measuring 3mJapanneed for more workspace.by 3m would be needed. The space for needed has beenearmarked.11 Reserved for major75,000 - - 0 numerous Local/ Europe/ USequipment followingprogress of project12 Glass Processing- 205,650 - 205,650 Approved at the VM LABEquipmentsPotential users/research groupsFrequency and intensity of usage810,000.00 505,650.00 185,000.00 690,650.008Emeritus Prof. Dr. Lam SaiKitSpecial Equipments1 Femtosecond laser 1,300,000 1,300,000 - 1,300,000 1 Japan/USA Femtosecond laser is a standard laser system for Currently several groups in UM are actively doing research Lab space available in HIR Building.Photonics and ultrafast science researchers in Frequently used (5 days per week) and eachresearch at the frontier of laser science that can in the field called ultrafast laser science and femtosecond Meeting with architect, mechanical & electrical physics, chemistry and biology.experiment will run up few hours to 1 day.produce a pulse of photons that is shorter than a laser. Without this equipment we cannot conduct high engineer done. Software included.Optical physics, femtosecond laser groups.picosecond.precision measurements at and beyond current state of the A medium size (10'x10') instrument, needs air-cond Able to generate results for Tier 1 papers such asExperiments utilizing that technique it is useful to art. This will impede HIR work on femtosecond studies and and clean room which is available. Without this Nature Photonics, PNAS, Science, Nature, as perobserve atomic in molecular processes in chemical the HIR researchers will be unable to publish work in top Tier instrument, no femto-second research can proceed. thephotonics and femtosecond laser researchers asreactions in gases, liquids and solids, and also in 1 journals in this area. Physicists and chemists in UM need Experience researcher will be hired to manage thementioned.catalytic processes and biological materials. This laser this instrument to study reactions which no instruments are use of the equipment for research. The price wasAt least 10 PhD and 20 MSc students will be trainedwill provide new tool to create attosecond pulse able to detect. Exisitng femtosecond system was refurbished obtained from quotation by vendor.per PI using this instrument. This unit will enabletechnology for imaging electronic states. It is widely from an old one has poor and unreliable performance, with Frequently used (5 days per week) and eachUM to create niche area in whole genome research.used in quantum nonlinear optics, multiphoton restricted features such as limited power to conduct many experiment will run up few hours to 1 day.spectroscopy and microscopy (fluorescencenovel nonlinear optics experiments. Thus, we need state ofmicroscopes), micro-machining, femtochemistry, the art femtosecond laser in UM, since it is a bottleneck andmedical imaging Terahertz (T-rays) generation and hindering all related work in UMdetection and frequency comb generation.2 High performance400,000 400,000 - 400,000 1 USA This is a versatile system handles gel sandwiches, agarose and Bacause it has highly sensitive optics enable directIt is a table top size instrument and hence requires biologist, pharmacologist,Frequently used (5 days per week) and eachblot imagerpolyacrylamide gels, membranes, microplates, and even chemiluminescent imagingno big space at the HIR Building.molecular biologist, chemists working in imaging of experiment will run up few hours to 1 day.microarrays. It has red-, green-, and blue-excitation without intermediate exposure to films or screens. Moreover, it has Software is included.that needs storage phosphor technology. All userswavelengths and a wide choice of emission filters enable automated four-color fluorescence scanning allows multiplexing of Routinely and frequently used (5 days per week) that work on data imaging involvingimaging of an extensive variety of fluorophores and sensitive multiple targets in the same sample ensuring accuracy of analysis, and each usage will take few hours daily.bioluminescence, chemiluminescence, fluoresence.detection of low-abundance targets. Storage phosphor increasing throughput, and saving time. With this unit, manyThis is a peripheral yet essential instruments totechnology delivers high-resolution imaging and accurate blotting and hybridization work (Western, Souther, Nothern,support all other high throughput instruments thatquantitation of 3H, 14C, 125I, 32P, 33P, 35S, and other colony dot blot) can be done effortlessly and save time, chemicals,require massive blot imaging.sources of ionizing radiation.labour and fast delivery of results. This save time from few days tohour and enable speedy process for HIR research.3 Microarray withscanner, nanoprinter,software androbotics arm1,600,000 1,600,000 - 1,600,000 1 USA/Germany DNA microarrays can be used to detect DNA (as in Only one old unit available in UM which is old and not Lab space available in HIR Building. Meeting with Potential users include biologist, pharmacologist, Due to the autamated operation, this instrument cancomparative genomic hybridization), or detect RNA upgradable,architect, mechanical & electrical engineer done. molecular biologist, medical scientists. This is the be frequently used (5 days per week) and each usage(most commonly as cDNA after reverse transcription) and unable to fulfil current research needs. Microarray and Software included to analyse global gene expression instrument that can capture genes expression will take few hours to 1 day.that may or may not be translated into proteins. The scanner are required and it is now regarded as "routine" and quantitation of gene activity. A room size of regulation at spatio-temporal manner, and useful toprocess of measuring gene expression via cDNA is instrument in technologically advance labs. UM researchers 15'x15' with air-con.all users ranging from cancer studies, cell cycle, tocalled expression analysis or expression profiling. need this to study global genes expression and spatiotemporalgenes/genome expression is only possible with the can proceed.This is the instrument routinelyWithout this instrument, no genome expression work bacterial and viral genomic work.Applications on gene expression profiling, ChiP, SNPAble to generate results for Tier 1 papers such asdetection, genome expression profiling and comparative availability of this instrument. Microarray data have been available in Caltech, Imperial College, ParisNature, Science, PNAS, for all the users of thisgenomes, drug action mechanism, DAMID etc. accepted for publication in reputable Tier 1 journal such as University, Nottingham, London University, UCL,instrument as mentioned.Nature Genetics, Cell, PNAS etc.Cambridge etc.At least 5 PhD and 10 MSc students will be trainedDue to the autamated operation, this instrument canbe frequently used (5 days per week) and eachper PI using this instrument. This unit will enableusage will take few hours to 1 day.UM to create niche area in whole genome research.4 GS FLX+ NGS/pyrosequencer2,400,000 2,400,000 - 2,400,000 1 USA The GS FLX+ System is a pyrosequencer that has FLX+ NGS pyrosequencer is the latest unit in the market Lab space available in HIR Building.Target users including biologist, pharmacologist, Routinely and frequently used, and typical run lastssequence genomes in short time, with thewhich is released in Nov 2011. No such instruments Meeting with architect, mechanical & electrical molecular biologist, medical scientists studying for 10 days. It is anticipated that this instrument willcombination of long reads, exceptional accuracy and in UM/ South East Asia. UM researchers need it to perform engineer done. Genome sequences and gene whole genome, metagnome, transcriptome, exome, be heavily use as only 3-10 runs per month ishigh-throughput, making the system well suited for personalised genome sequencing, and plant, animal, annotation, analysis softwares are included. A room epigenetics sequencing, genes expression and possible.larger genomic projects. Advancements in sequencing bacteria whole genome sequencing can only be done using size of 13'x13' with air-con. Without this instrument, analysis. This is the instrument that can performchemistry, instrumentation and software offer the latest this instrument. This instrument since its invention few years no genome sequencing research can proceed. whole genome sequencing in less than 1 week. It isimprovements in GS FLX System performance, with back, it has made it to Nature, Science, J. Bacteriology, etc. Routinely and frequently used, and typical run lastsalso useful to all users ranging working on cancerread lengths up to 1 kb.for 10 days. It is anticipated that this instrument willstudies to microbial genomic work.be heavily use as only 3-10 runs per month isAt least 10 PhD and 20 MSc students will be trainedpossible.per PI using this instrument. This unit will enableUM to create niche area in whole genome research.- updated on 2nd March 2012 -