Clinical Trials

■■❚❙❘Chapter 24Regression AnalysisFiona Steele and Duolao WangMost medical events have multiple causes, and these causesare often related. Multiple regression analysis is a statistical toolthat has become increasingly important for medical research.It is used to determine the relationship between a single eventor outcome and its different causes. These causes can thenbe established as risk factors for the occurrence of events orprotective factors for the prevention of events. In this chapter,we introduce three commonly used types of regression analysis –linear, logistic, and hazards regression – and focus on practicalissues, such as when to apply each method and how to interpretthe results.273