Obesity Epidemiology

(A)(B)Relative risk of deathCancer Prevention Study II2.82.62.42.22.01.81.61.41.21.00.80.6MenCurrent or former smokerswith a history of diseaseNonsmokers with no history of disease18.518.5-20.420.5-21.922.0-23.423.5-24.9Body mass indexNurses’ Health StudyAll women, 1976-199225.0-26.426.5-27.928.0-29.930.0-31.932.0-34.935.0-39.940.0Relative risk of death2.22.01.81.61.41.21.00.80.618.518.5-20.4WomenCurrent or former smokerswith a history of diseaseNonsmokers with no history of disease20.5-21.922.0-23.423.5-24.925.0-26.4Body mass index26.5-27.928.0-29.930.0-31.932.0-34.935.0-39.940.0Women who never smoked and had stable weight, 1980-1992Age-adjusted relative risk2.52.01.51.00.5Multivariable relative risk2.52.01.51.00.53.2 3.40.019.019.0-21.922.0-24.925.0-26.927.0-28.929.0-31.9320.019.019.0-21.922.0-24.925.0-26.927.0-28.929.0-31.932Body mass indexBody mass index(C)National Institutes of Health-AARP Diet and Health StudyRelative risk of death4.543.532.521.510.50All men, baseline BMIMen who never smokedBMI at age 5018.518.5-20.921.0-23.423.5-24.825.0-26.426.5-27.928.0-29.930.0-34.935.0-38.9Body mass index40Relative risk of death4.543.532.521.510.5018.518.5-20.9All women, baseline BMIWomen who neversmoked BMI at age 5021.0-23.423.5-24.825.0-26.4Body mass index26.5-27.928.0-29.930.0-34.935.0-38.940Figure 11.3 The relationships between BMI and mortality in three cohort studies: CancerPrevention Study II, Nurses’ Health Study, and National Institute of Health-AARP Diet andHealth Study. Reproduced with permission from Manson JE, Bassuk SS, Hu FB, Stampfer MJ,Colditz GA, Willett WC. Estimating the number of deaths due to obesity: can the divergentfindings be reconciled? Women’s Health. 2007;16(2):168-176. 1223