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Obesity Epidemiology

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482 EPIDEMIOLOGIC STUDIES OF DETERMINANTS OF OBESITY25. Memisoglu A, Hu FB, Hankinson SE, et al. Interaction between a peroxisome proliferator-activatedreceptor gamma gene polymorphism and dietary fat intake in relationto body mass. Hum Mol Genet. 2003;12:2923-2929.26. Robitaille J, Despres JP, Perusse L, Vohl MC. The PPAR-gamma P12A polymorphismmodulates the relationship between dietary fat intake and components of the metabolicsyndrome: results from the Quebec Family Study. Clin Genet. 2003;63:109-11627. Kubota N, Terauchi Y, Miki H, et al. PPAR gamma mediates high-fat diet-inducedadipocyte hypertrophy and insulin resistance. Mol Cell. 1999;4:597-609.28. Yamauchi T, Waki H, Kamon J, et al. Inhibition of RXR and PPARgamma amelioratesdiet-induced obesity and type 2 diabetes. J Clin Invest. 2001;108:1001-1013.29. Krey G, Braissant O, L’Horset F, et al. Fatty acids, eicosanoids, and hypolipidemicagents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependentreceptor ligand assay. Mol Endocrinol. 1997;11:779-791.30. Nieters A, Becker N, Linseisen J. Polymorphisms in candidate obesity genes and theirinteraction with dietary intake of n-6 polyunsaturated fatty acids affect obesity risk ina sub-sample of the EPIC-Heidelberg cohort. Eur J Nutr. 2002;41:210-221.31. Robitaille J, Gaudet D, Perusse L, Vohl MC. Features of the metabolic syndrome aremodulated by an interaction between the peroxisome proliferator-activated receptordelta−87T>C polymorphism and dietary fat in French-Canadians. Int J Obes (Lond).2006;31(3):411-417.32. Robitaille J, Houde A, Lemieux S, Perusse L, Gaudet D, Vohl MC. Variants withinthe muscle and liver isoforms of the carnitine palmitoyltransferase I (CPT1) geneinteract with fat intake to modulate indices of obesity in French-Canadians. J MolMed. 2007;85:129-137.33. Corella D, Lai CQ, Demissie S, et al. APOA5 gene variation modulates the effectsof dietary fat intake on body mass index and obesity risk in the Framingham HeartStudy. J Mol Med. 2007;85(2):119-128.34. Marti A, Corbalan MS, Martinez-Gonzalez MA, Forga L, Martinez JA. CHO intakealters obesity risk associated with Pro12Ala polymorphism of PPARgamma gene.J Physiol Biochem. 2002;58:219-220.35. Martinez JA, Corbalan MS, Sanchez-Villegas A, Forga L, Marti A, Martinez-GonzalezMA. <strong>Obesity</strong> risk is associated with carbohydrate intake in women carrying theGln27Glu beta2-adrenoceptor polymorphism. J Nutr. 2003;133:2549-2554.36. Miyaki K, Sutani S, Kikuchi H, et al. Increased risk of obesity resulting from theinteraction between high energy intake and the Trp64Arg polymorphism of the beta3-adrenergic receptor gene in healthy Japanese men. J Epidemiol. 2005;15:203-210.37. Vaccaro O, Lapice E, Monticelli A, et al. Pro12Ala polymorphism of the PPARgamma2locus modulates the relationship between energy intake and body weight intype 2 diabetic patients. Diabetes Care. 2007;30(5):1156-1161.38. Song Y, Miyaki K, Araki J, Zhang L, Omae K, Muramatsu M. The interactionbetween the interleukin 6 receptor gene genotype and dietary energy intake onabdominal obesity in Japanese men. Metabolism. 2007;56(7):925-930.39. Santos JL, Boutin P, Verdich C, et al. Genotype-by-nutrient interactions assessed inEuropean obese women: a case-only study. Eur J Nutr. 2006;45:454-462.40. Meirhaeghe A, Helbecque N, Cottel D, Amouyel P. Beta2-adrenoceptor gene polymorphism,body weight, and physical activity. Lancet. 1999;353:896.41. Corbalan M, Marti A, Forga L, Martinez-Gonzalez MA, Martinez JA. The 27Glupolymorphism of the beta2-adrenergic receptor gene interacts with physical activityinfluencing obesity risk among female subjects. Clin Genet. 2002;61:305-307.42. Marti A, Corbalan MS, Martinez-Gonzalez MA, Martinez JA. TRP64ARG polymorphismof the beta 3-adrenergic receptor gene and obesity risk: effect modification by asedentary lifestyle. Diabetes Obes Metab. 2002;4:428-430.43. Ricquier D, Bouillaud F. Mitochondrial uncoupling proteins: from mitochondria to theregulation of energy balance. J Physiol. 2000;529(Pt 1):3-10.

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