reSOLUTION_Research_09_Neuroscience - Leica Microsystems

stereotaXic
36 resolutioN
microsystems) has led to development of a novel impact
device with a remote actuator that can be mounted
on a small animal stereotaxic instrument, and take
advantage of the instrument’s precise positioning and
angle capabilities.
today, leica microsystems offers the new leica impact
one, together with the most advanced stereotaxic
instrument, leica angle two. With the stereotaxic instrument,
the extended impact tip may be positioned
relative to skull landmarks, and at any angle. it is then
retracted, and, again with the stereotaxic instrument,
advanced toward the preplanned maximum penetration
depth. the operator can then fire an impact upon
either skull or the exposed brain or spinal cord.
the leica impact one, mounted on a stereotaxic instrument,
can precisely control the position and angle
of impact, dwell time (the time the tip remains in
contact), and velocity of impact in a very reproducible
way. this represents a significant advance in the precision
and reproducibility of instrumentation available
to study the results of impacts on neural tissue.
The new Leica Impact One –
enhances accuracy and reproducibility of
controlled cortical or skull impact
• Position and reproducible positioning of impact (via stereotaxic instrument)
• mounts on an existing stereotaxic instrument
• control of impact probe terminal velocity
• control of dwell time
• control (via stereotaxic) maximum penetration depth
References
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impact device for Precise, graded experimental traumatic brain
injury. Journal of neurotrauma apr 2007, Vol. 24, no. 4 : 657 -673
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