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BioWorld® - Medical Device Daily

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BioWorld Industrial Biotechnology StatReport: Immediate and Comprehensive Industry Information<br />

BUSINESS STRATEGY: Diversa delivers unparalleled enzyme performance for alternative fuels,<br />

industrial, and health/nutrition processes. Diversa’s patented gene mining<br />

and DirectEvolution technologies have yielded the world’s largest bank of<br />

biodiverse enzymes. These enzymes enable manufacturers to make<br />

products more efficiently and inexpensively while protecting the<br />

environment. Diversa’s goal is to be the leadiing provider of industrial<br />

enzymes and biologically active compounds for use in unique, economically<br />

attractive applications.<br />

The key elements of Diversa’s strategy are to:<br />

Further enhance their technology leadership position<br />

Continue strong focus on alternative fuel markets<br />

Expand their existing DNA libraries through access to novel genetic material<br />

and utilize our proprietary technologies to discover new genes and gene<br />

pathways<br />

Deploy their technologies across diverse markets in order to maximize their<br />

return on investment<br />

Pursue additional strategic alliances with market leaders to access funding<br />

and industry-specific expertise<br />

Independently develop and commercialize products in specific markets to<br />

capture their full economic value<br />

Discover, modify and commercialize protein-based enzyme catalysts for<br />

chemical synthesis and industrial processes<br />

Discover new lead drug compounds from bioactive pathways in<br />

microorganisms and transgenic application of enzymes to plants for insect<br />

and disease control<br />

AGREEMENTS: Name Products Content of Agreement Date<br />

BASF AG Diversa to discover and<br />

optimize new enzymes,<br />

BASF responsible for<br />

product and process<br />

development and<br />

commercialization<br />

alliance 2/06<br />

Cargill Health and enzymes for the cost- discovery and 4/05<br />

Food<br />

effective production of a development<br />

Technologies proprietary product agreement<br />

Merck & Co. Inc. therapeutic antibodies development 1/05<br />

using Diversa's MedEv agreement,<br />

platform<br />

expanded 6/05<br />

RESEARCH & DEVELOPMENT: Alternative energy<br />

Specialized industrial processes<br />

Health and nutrition<br />

PRODUCTS ON MARKET: Valley Ultra-Thin improves ethanol production<br />

Luminase enzyme<br />

Phyzyme XP enzyme (for pigs and chickens)<br />

Quantum Phytase (for pigs and chickens)<br />

Pyrolase 160 enzyme<br />

ThermalAce DNA Polymerase<br />

Bayovac® SRS (vaccine for farmed salmon, available in Chile)<br />

PRODUCTS IN DEVELOPMENT: Name Status<br />

Sordarins antifungal in preclinicals<br />

Purifine (converts biomass to biofuel) in development<br />

Amylase-T in regulatory review (U.S.)<br />

Enzyme cocktail for cellulosic ethanol<br />

production (unnamed)<br />

in development<br />

Phytase-T in development<br />

Various antibodies, anti-SARs, anti-anthrax<br />

and anti-plague antibodies<br />

in development<br />

Copyright ©2006 AHC Media ® 135

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