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BioWorld Industrial Biotechnology StatReport: Immediate and Comprehensive Industry Information Hebrew University of Jerusalem I.R.D. (Institute of R&D) extremophilic microorganism extremophilic microorganism Ifremer extremophilic microorganism Russian Academy of Science extremophilic microorganism Thales systems for detection and identification of biological attack University of Bern chemistry for high throughput funcitonal University of Buenos Aires screening extremophilic microorganism screening for novel enzyme from extremophilic microorganism screening for novel enzyme from extremophilic microorganism screening for novel enzyme from extremophilic microorganism screening for novel enzyme from extremophilic microorganism Copyright ©2006 AHC Media ® 332 1999 1999 1999 2005 R&D agreements 1999 2000 2002 collaborative R&D agreements screening for novel enzyme from extremophilic microorganism RESEARCH & DEVELOPMENT: Novel proteins, novel industrial enzymes, new industrial chemo-biocatalytoc routes, biodiversity screening, protein engineering, development of gene based assay for the industry Qbiogene 15 Morgan Irvine CA 92618-2005, Canada Phone: (440) 337-1200; Fax: (949) 421-2675 Toll-free phone: (800) 854-0530 Web: www.qbiogene.com E-mail: info@qbiogene.com KEY PERSONNEL: Milan Panic; Chairman and CEO, MP Biomedicals Dr. Garth Cumberlidge; President and CEO Steve Peronne; CFO EMPLOYEES: 250 employees HISTORY: Founded in 1991 Began biotech R&D in 1993 Began sales in 1996 Aquired Appligene-Oncor, Strasbourg, France Merged with Bio-101, Inc. and changed name from Quantum Biotechnologies (7/00) Acquired Alexis Biochemicals, Switzerland Acquired Bio-101, Carlsbad, California Acquired by MP Biomedicals STOCK-FINANCIAL HISTORY: Privately held SUBSIDIARY OF: MP Biomedicals BUSINESS STRATEGY: Develop and market novel and innovative products for gene delivery, gene therapy applications and molecular biology applications related to the study of the structure and function of the human genome 2003 2000 2004 2005
BioWorld Industrial Biotechnology StatReport: Immediate and Comprehensive Industry Information AGREEMENTS: Name Products Content of Agreement Date BTC nucleotides, enzymes, probes supply agreement 1995 Hoffmann-La native and recombinant development, 3/98 Roche Ltd./Perkin- Taq DNA polymerase manufacturing and Elmer Corp. and other thermostable marketing enzymes for use in polymerase chain reaction process agreement INRA CNRS baculovirus expression technology 1996 systems development agreement NCI AFP expression vectors distribution license and CRADA 1996 NRC Canada adenovirus expression exclusive 2/92 system worldwide agreement NRC Canada recombinant yeast lytic exclusive 10/91 enzyme worldwide agreement NRC Canada site-directed exclusive 10/91 mutagenesis worldwide agreement Universite de pGATA cloning system technology 1996 Montreal development agreement RESEARCH & DEVELOPMENT: Gene delivery systems Custom services - Adinoviral PRODUCTS ON MARKET: FISH kits and buffers DNA polymerases Baculovirus expression system and custom services Peptide coupling reagents Cloning vectors Gene delivery systems DNA panels Yeast lytic enzyme Adenovirus and bacterial (Alkaline Phosphatase [PhotA*} fusion)expression systems Autofluorescent proteins Positive selection vector Custom peptide synthesis Embyonal tissue mRNAs and cDNAs Custom services (Adenovirus, antibodies and peptides) Bio-101 systems Media Purification--DNA/RNA Fast Prep system PRODUCTS IN DEVELOPMENT: Name Status Second-generation adenoviral vectors in development Transfection systems in development Two-hybrid systems in development Copyright ©2006 AHC Media ® 333
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