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BioWorld® - Medical Device Daily

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BioWorld Industrial Biotechnology StatReport: Immediate and Comprehensive Industry Information<br />

Bayer AG Genzyme's small<br />

molecule library<br />

licensing<br />

agreement--<br />

Genzyme will<br />

receive up-front<br />

and service fees<br />

and milestones<br />

Copyright ©2006 AHC Media ® 177<br />

12/97<br />

Behringwerke AG amylase substrate licensing<br />

agreement<br />

11/91<br />

Biogen Idec Inc. Avonex (interferon beta- commercialization 9/98<br />

1a) for MS<br />

and exclusive<br />

distribution<br />

agreement for<br />

Japan<br />

Celtrix<br />

TGF-B2 for tissue product<br />

6/94<br />

Pharmaceuticals repair, treatment of MS, development,<br />

Inc.<br />

and other systemic licensing, and<br />

applications<br />

marketing<br />

agreement through<br />

Genzyme Tissue<br />

Repair<br />

Crucell NV production of<br />

nonexclusive STAR 12/05<br />

monoclonal antibodies research licensing<br />

agreement<br />

Cubist<br />

small molecule<br />

drug discovery 3/97<br />

Pharmaceuticals compounds targeting alliance--Cubist will<br />

Inc.<br />

bacterial and fungal screen Genzyme's<br />

infections<br />

compound library,<br />

once potential<br />

therapeutic<br />

compounds are<br />

discovered, Cubist<br />

and Genzyme will<br />

negotiate<br />

development terms<br />

Cyclacel Group Licensing of two of option agreement 9/05<br />

plc<br />

Cyclacel's Cyclin-<br />

Dependent Kinase<br />

inhibitors<br />

Daiichi Pure HDL cholesterol blood distribution<br />

1/96<br />

Chemicals Co.<br />

Ltd.<br />

test<br />

agreement<br />

De Novo<br />

De Novo to apply its drug discovery 1/06<br />

Pharmaceuticals molecular structure collaboration<br />

Ltd.<br />

generating technology<br />

to focus on a disease<br />

target that is of interest<br />

to Genzyme<br />

agreement<br />

DiagnoCure Inc. 40 genes for potential licensing<br />

11/05<br />

use in detecting lung<br />

cancer<br />

agreement<br />

Dyax Corp. Dyax's phage display non-exclusive 1996<br />

patents<br />

patent licensing<br />

agreement,<br />

including signing<br />

fees, milestone<br />

payments and<br />

royalties, Dyax gets<br />

access to related<br />

patented<br />

technology owned<br />

by licensee<br />

Dyax Corp. Dyax's human plasma letter of intent for 12/98<br />

Kallikrein inhibitor (EPI- development<br />

KAL-2)<br />

agreement

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