Review of the Air Quality Criteria Document for Particulate Matter

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7-1 15-22 change "translocated" to "clearance" and vice-versa. Theusage of these terms is in error, and is inconsistent withusage later in the chapter.7-3 1 insert "components of" before "aerosols".7-3 14 delete "a", and insert an "s" after "parameter".7-3 16 insert "from specific sources" after "aerosols". The ambientaerosol is generally composed of multiple log-normaldistributions of aerosols from specific sources.7-3 18 change "σg" to "σg".7-3 19 change "(or 16th % particle size to the 50th % size" to "%particle size to the 50th % size, or the 50th % to the 16th %size"".7-3 20 delete "aerosol", and insert "of a specific aerosol" after "sizes".7-4 21 delete "cellular", and insert "cells of airway surfaces in the"before "ET".7-5 11 change "1 :m" to "2 :m".7-5 13 change ">0.5 :m" to ">1 :m".7-5 19 change "lower" to "smaller" and delete "largest".7-5 20 change ", which" to "that".7-5 28 change "0.3 to 0.5" to "0.2 to 1.0".7-6 4 insert ", but their length is the factor that determinesinterception deposition" after "length".7-6 6 delete "when it is electrically neutral". This is an entirelyredundant statement.7-6 9 insert "generally" before "lose".7-6 10 delete "slowly"7-6 14 insert "positive and negative" before "charges".7-6 15 change "some particles may result in an" to "particleswill result in".7-6 20 change "probably" to "often".7-7 23 insert "ET" before "deposition".7-7 30 change "0.3 to 0.5" to "0.2 to 1.0".A - 41
7-12 8 insert "that are either very large or very small" after"particles".7-12 19-26 The data that are cited here should be described in greaterdetail and/or presented here in terms of a graph or table.7-13 8 Reference should be made here to the work of Brody et al.(ARRD 123:670-699, 1981); Brody and Roe (ARRD 128:724-729, 1983); and Warheit et al. (Exp. Lung Res. 16:83-99, 1990)indicating that particles also deposit preferentially atbifurcations of alveolar ducts in small animals.7-13 23 insert "distal to the larynx" after "volume".7-14 16 insert "average" before "surface".7-14 19 insert ", and furthermore do not take the concentration ofdeposition on carinal ridges into account" after "effects".7-14 28 insert "The thoracic fraction of the" before "coarse".7-15 3,5,6,14 change "NP" to "ET" for consistency with previous text inthis chapter.7-15 14 change "lungs" to "respiratory tract".7-16 20 change "differ in" to "have different", and insert"distributions" after "parameter".7-17 25 insert "large airway" after "increased".7-28 9 change "deposition" to "retention".7-28 12 insert "at the respiratory acini" after "tissue". Theimportance of the existence of respiratory bronchioles inhumans, but not in rodents, should be discussed at thispoint.7-28 30 insert "for specific surface regions" before "that".7-34 4-5 The sentence is incomplete.7-37 2 insert "toxicant" before "exposure".7-44 21 This discussion is incomplete without a further elaborationof the fact that inhalation exposure results in concentrationsof deposited particles on the bifurcations of both large andsmall airways.7-52 31 This discussion is incomplete without a further reference toNikola et al. (2000), which compared retention sites in labanimals (surficial) to humans (interstitial).A - 42
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Review of the Air Quality Criteria Document for Particulate Matter

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