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Review of the Air Quality Criteria Document for Particulate Matter

Review of the Air Quality Criteria Document for Particulate Matter

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atmospheric stressors associated with PM should be included as well. These wouldinclude base cations, hydrogen ions, heavy metals, pesticide residues, oxidants, etc. Analternative would be to simply list <strong>the</strong>se as part <strong>of</strong> <strong>the</strong> deposition process but not relevantto <strong>the</strong> CD.15. The processes discussed governing how PM affects vegetation are only a fragment <strong>of</strong> <strong>the</strong>physics, chemistry and biology <strong>of</strong> PM. The concepts to be included should be effects <strong>of</strong>velocity and particle size on deposition, solubilization, evapoconcentration, rainfallevents, wash <strong>of</strong>f, re-suspension, transcuticular migration, etc.16. Deposition to surface waters is entirely missing in <strong>the</strong> CD and yet this is a major issue <strong>for</strong>understanding estuaries and lakes. There is a host <strong>of</strong> data <strong>for</strong> this topic <strong>for</strong> majorresources and <strong>the</strong> largest set <strong>of</strong> data is <strong>for</strong> <strong>the</strong> Great Lakes. Its omission in light <strong>of</strong> whatis included (e.g., nitrogen and sulfur at IFS sites) is a problemRonald H. White, M.S.T.Chapter 6: Epidemiology <strong>of</strong> Human Health Effects from Ambient <strong>Particulate</strong> <strong>Matter</strong> -General CommentsOverall, this chapter presents a comprehensive review <strong>of</strong> <strong>the</strong> extensive body <strong>of</strong>epidemiological studies published since completion <strong>of</strong> <strong>the</strong> 1996 particulate matter criteriadocument. The chapter properly interprets <strong>the</strong> studies discussed and appropriately emphasizes<strong>the</strong> strengths and weaknesses <strong>of</strong> <strong>the</strong> current scientific evidence <strong>of</strong> <strong>the</strong> health effects <strong>of</strong> particulatematter.One key issue that requires fur<strong>the</strong>r attention is <strong>the</strong> need <strong>for</strong> a consistent approach wi<strong>the</strong>xplicit criteria throughout <strong>the</strong> chapter <strong>for</strong> <strong>the</strong> selection <strong>of</strong> <strong>the</strong> analyses from <strong>the</strong> studies included<strong>for</strong> summarization in <strong>the</strong> tables. For example, <strong>the</strong>re are several criteria described (pg. 184; lines8 –17) as providing <strong>the</strong> basis <strong>for</strong> selection <strong>of</strong> <strong>the</strong> analyses summarized in Table 6-19 and 6-20.However o<strong>the</strong>r summary tables do not explicitly provide <strong>the</strong> criteria <strong>for</strong> <strong>the</strong> selection <strong>of</strong> analysessummarized in <strong>the</strong> tables. Providing <strong>the</strong>se criteria make <strong>the</strong> approaches used in selecting <strong>the</strong>analyses included <strong>for</strong> summarization in <strong>the</strong>se tables and avoid concerns regarding author bias in<strong>the</strong> selection <strong>of</strong> analyses included <strong>for</strong> summarization.The discussion <strong>of</strong> <strong>the</strong> infant mortality/related morbidity studies that have been publishedsince 1996 should be expanded. These data are important new findings that significantlyaugment <strong>the</strong> more limited data available in <strong>the</strong> 1996 CD. A table summarizing <strong>the</strong>se studiesshould also be included in <strong>the</strong> chapter.The discussion <strong>of</strong> lung cancer associated with PM exposure in <strong>the</strong> long-term prospectivestudies should be expanded and receive additional attention in <strong>the</strong> text. Given <strong>the</strong> finding <strong>of</strong> astatistically significant association <strong>of</strong> PM and lung cancer in <strong>the</strong> recent expanded ACS studyanalysis by Pope, which I would presume will be included in <strong>the</strong> next revision <strong>of</strong> <strong>the</strong> CD, thishealth endpoint deserves substantial fur<strong>the</strong>r elaboration and emphasis. In addition, <strong>the</strong> entirediesel particulate health effects literature regarding lung cancer is not referred to in thisdiscussion. Recognizing that <strong>the</strong> EPA Diesel <strong>Particulate</strong> Health Assessment document reviewsthis literature in detail, <strong>the</strong> relevant science should be summarized in this chapter’s discussion <strong>of</strong><strong>the</strong> lung cancer issue and <strong>the</strong> reader referred to <strong>the</strong> Diesel Health Assessment document <strong>for</strong> amore complete discussion <strong>of</strong> this scientific literature.Specific CommentsPg. 6-226: This discussion regarding alternative methodological approaches to addressingconfounding omits reference to <strong>the</strong> selection <strong>of</strong> study areas where potentially confounding airpollutant levels are relatively low (e.g. Vedal’s 1998 study <strong>of</strong> asthmatic and nonasthmaticchildren in Port Albeni, B.C.).Appendix 6A and 6B: There is no explanation in Chapter 6 as to <strong>the</strong> rationale <strong>for</strong> <strong>the</strong> inclusion <strong>of</strong>A - 80

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