2,4,6-trinitrotoluene (TNT) - OEHHA
2,4,6-trinitrotoluene (TNT) - OEHHA
2,4,6-trinitrotoluene (TNT) - OEHHA
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Genotoxicity of <strong>TNT</strong> Metabolites<br />
2-ADNT 4-ADNT 2,4-DANT 2,6-DANT<br />
Salmonella mutation<br />
assays (TA 98, TA100) + + + +<br />
CHO-HPRT<br />
mutation assay<br />
V79-HGPRT<br />
mutation assay<br />
4-NHOH-DNT<br />
- + (S9) - + (weak)<br />
- + (weak) - -<br />
- Positive: in vitro oxidative DNA damage (8-oxodG);<br />
cleaves DNA at sites with consecutive guanines<br />
Office of Environmental Health Hazard Assessment
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