2,4,6-trinitrotoluene (TNT) - OEHHA
2,4,6-trinitrotoluene (TNT) - OEHHA
2,4,6-trinitrotoluene (TNT) - OEHHA
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18<br />
Urine Mutagenicity<br />
• Rats treated with <strong>TNT</strong><br />
—Positive in Salmonella<br />
• Humans exposed to <strong>TNT</strong><br />
—Increased mutagenicity in Salmonella of<br />
urine from exposed as compared with<br />
unexposed controls<br />
—Higher in NAT1 rapid vs. slow acetylators<br />
Office of Environmental Health Hazard Assessment