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2,4,6-trinitrotoluene (TNT) - OEHHA

2,4,6-trinitrotoluene (TNT) - OEHHA

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21<br />

Authoritative Body Reviews<br />

• US EPA (1993)<br />

—Reviewed animal studies by Furedi et al. (1984a,b)<br />

—Did not include any human studies<br />

—Did not include several studies on metabolism, genotoxicity,<br />

biomarkers of exposure<br />

—Group C: “possible human carcinogen”<br />

• IARC (1996)<br />

—Did not include the epidemiology studies of Kilian et al. (2001),<br />

Yan et al. (2002)<br />

—Did not include animal cancer studies<br />

—Did not include several recent studies on metabolism,<br />

genotoxicity, biomarkers of exposure<br />

—Group 3: “not classifiable as to carcinogenicity in<br />

humans”<br />

Office of Environmental Health Hazard Assessment

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