<strong>June</strong> <strong>2007</strong>KUWAIT MEDICAL JOURNAL 145Fig. 1: Algorithmic approch to Blunt Splenic TraumaTable 1: ASST* splenic <strong>org</strong>an injury scaleCLASS ICLASS IICLASS IIICLASS IVCLASS VHematoma subcapsular < 10% surface area lacerationcapsular tear < 1 cm parenchymal depthHematoma subcapsular 10 - 50% surface areaIntraparenchymal < 5 cm diameterLaceration 1 - 3 cm parenchymal depth not involving aparenchymal vesselHematoma subcapsular > 50% surface area or expandingRuptured subcapsular or parenchymal hematomaIntraparenchymal hematoma > 5 cmLaceration > 3 cm parenchymal depth or involvingtrabecular vesselsLaceration of segmental or hilar vessels producing majordevascularization (> 25% of spleen)Laceration completely shattered spleenHilar laceration injury which devascularized spleen* American Society for the Surgery of Traumaimaging investigations, associated injuries, bloodtransfusion, complications, treatment and surgicalprocedures, morbidity, mortality and hospital stay.The patients were divided into two groups; theoperative management group included patientswho were hemodynamically unstable and requiredexploratory laparotomy. The surgical procedureswere either splenectomy, splenorrhaphy or partials p l e n e c t o m . y The NOM was applied inhemodynamically stable patients on presentationor who were hypotensive and stabilized withminimal intravenous fluids in emergency room.The patients with blunt splenic trauma weremanaged according to the algorithm shown in Fig.1. The diagnosis of intraperitoneal hemorrhage wasconfirmed by diagnostic peritoneal lavage (DPL) orpositive abdominal ultrasonogram (USG) for freeintraperitoneal fluids in hemodynamically unstablepatients. The imaging modalities employed forh e m o d y n a m i c a l l ystable patients were abdominalultrasonogram and CT scan of the abdomen. Thesplenic injuries were classified according to thesplenic injury scale of the American Society for theSurgery of Trauma (ASST) (Table 1). Patients withhigh class injuries were admitted to the IntensiveCare Unit (ICU) for close monitoring for the first 48hours with serial clinical examinations andhemoglobin checkup. Patients with isolated splenicminor injuries were observed in the surgical wardwith close monitoring. Patients were kept on bedrest for 5-7 days. The failure of NOM wasc o n s i d e red when the patient became hemodynamicallyunstable during observation or required more thantwo units of blood transfusion for splenic injury.They underwent exploratory laparo t o m y. Theoutcome of both groups was compared withemphasis on the patients’ age, class of injuries,numbers of blood transfusion, morbidity, mortalityand hospital stay. Statistical analysis was carriedout employing exact Fisher test, Chi-square test,and analysis of variance for comparative analysis ofthe data using IBM-compatible PC and SPSS 10.0for Windows (SPSS Inc., Chicago).RESULTSA total of 83 patients with splenic injuries due toblunt abdominal trauma were treated at the RiyadhMedical Complex over the five year period underreview. There were 72 men and 11 women. Themean age was 23.5 years (range 4-63 years). Themechanisms of injury were as follows: motorvehicle accident in 60 patients, fall from height in 13and sport injuries in 10 patients.Thirty five patients were hemodynamicallyunstable and underwent exploratory laparotomy(operative management group) due to ongoingbleeding from the injured spleen. The remaining 48patients were hemodynamically stable and wereselected for NOM.Thirty five patients underwent exploratoryl a p a rotomy due to ongoing intraperitonealhemorrhage. There were 30 male and 5 femalepatients. The mean age was 24 years (4 - 63 years).Seven patients were less than 13 years of age. Allpatients presented to emergency room withhypovolemic shock. DPL was performed in 30patients and was positive. The other five patientsunderwent USG which showed free intraperitonealfluid. The associated injuries were as follow:thoracic injuries in 18, extremities injuries in 11,head injuries in nine, spinal injuries in two, andpelvic injury in two patients. The associated intraabdominalinjuries were liver in seven,retroperitoneal hematoma in five, mesenteric tearin four, renal injuries in two, duodenum in one,diaphragm in one, and pancreas in one patient. Theclass of splenic injuries were low and moderate in
146Outcome of Non-operative Management of Blunt Splenic Trauma <strong>June</strong> <strong>2007</strong>Table 2: Comparative analysis of operative and NOMgroupsOperative (n = 35, 42%) NOM (n = 48, 57.8%)Age < 13 years: 7 patients Age < 16 years: 13, p < 0.000001Associated injuries ↑ Associated injuries (1 injury /(1.6 injury /patient) patient)Injuries grade:Injuries grade:Severe (IV, V) 40% Severe (IV, V) 23%, p = 0.1519Blood transfusion: all patients Blood transfusion: only 18(100%) patients (37.5%)Received (1 - 10 units)Received (1 - 6 units)Mean: 3.7 units per patient Mean: 0.8 units per patient, p = 0.015Hospital stay (7 - 61) days Hospital stay (3 - 32) daysMean 18.6 days Mean 11.2 days, p = 0.008Complication ↑ Failure: 4 patients (8.33%)Death : 5(severe head injury)Death : No21 patients (I in 3, II in 8 and III in 10) and high in14 patients (class IV in 8, class V in 6).Splenectomy was performed in 25 patients,splenorrhaphy in seven and partial splenectomy int h ree patients. All patients received bloodtransfusion. The average number of blood unitstransfused was 3.7 units /patient (range 1-10 units).Postoperative complications included atelectasis insix patients, pleural effusion in five, urinary tractinfection in five, chest infection in four, hematomain splenic bed in two, wound hematoma in two andwound infection in one patient. One patientsdeveloped complete adhesive bowel obstruction at10th postoperative day and required laparotomyfor adhesiolysis. The mean hospital stay was 18.6days (range 7 - 61 days). Five patients died due tosevere head injuries and multiple trauma and themortality rate in this group was 14 %.Forty eight patients were hemodynamicallystable and were treated conservatively. There were42 male and six female patients with a mean age of21 years (range 5 - 51years). Sixteen patients wereunder 13 years. Ten patients presented with shock.They were resuscitated and stabilized withintravenous fluids (mean 1.75 l / patient, range: 1.5- 2.5 l / patient) and blood transfusion. Eighteenpatients (37.5%) received blood transfusion. Themean number of blood units transfused was 0.8units / patient (range: 1 - 6 units). The remaining 38patients were hemodynamically stable atpresentation. Abdominal USG was performed in 28patients. It was able to detect splenic trauma in 24patients and showed free intraperitoneal fluids inrest of cases with a sensitivity of 85%. A nabdominal CT scan was performed in all patients toconfirm and classify the splenic injuries. The classof injury were as follows: low and moderate in 37patients (class I in 13, class II in 16, class III in 8)and high class in 11 (class IV in 8, class V in 3)a c c o rding to the CT findings. The associatedinjuries were as follows: thoracic injuries in 22,extremities in six, head injury in nine, spinal int h ree and pelvis in two patients. The intraperitonealinjuries were as follows: liver injuries in three (classI in 1, class II in 2), retroperitoneal hematoma intwo, pelvic hematoma in one and renal trauma intwo patients. The mean hospital stay was 11.2 days(range: 3-32 days). The NOM was successful in 44patients (91.7%). Four patients becamehemodynamically unstable after initial period ofconservative treatment. They required exploratorylaparotomy and splenectomy with failure rate ofNOM of 8.3%. All patients with NOM failure wereabove 13 years; two had class IV, one class V andone class III trauma.Comparison of outcome in both operative andNOM groups (Table 2) showed that the operativegroup had a relatively less number of pediatricpatients (20 Vs 33% for NOM patients; p =0.000001). The number of associated injuries washigher in the operative group (1.6 injuries / patientVs 1 injury / patient in NOM group). As regard theseverity of injury, the operative group had a higherclass (V, IV) of injuries than NOM group (40 Vs23%). The incidence of low and moderate classinjury (I, II, III) in the operative group was 60% ascompared to 77% in non-operative group (p =0.1519). All operative group patients received blood(100%) as against only 18 (37.5%) in NOM group.The blood transfusion rate was 3.7 units / patient inoperative group and 0.8 units / patient in NOMgroup (p = 0.015). The hospital stay was longer inoperative group (18.6 days Vs 11.2 days in NOMgroup, p = 0.008). There was no mortality in NOMgroup, while five patients died in the operativegroup. These patients had severe head injuries andpolytrauma (5 injuries / patient).DISCUSSIONThe management of splenic trauma has evolvedwith time, from splenectomy towards splenicpreservation and NOM over the last 25 years. Thesusceptibility to infection and post-splenectomysepsis was well established early in the 20thc e n t u r y [ 1 , 2 ] . Green et al reported major septiccomplications rate of 5.9% (pneumonia, septicemia,meningitis) in post-splenectomy patients [ 1 2 ] . Theoverwhelming post-splenectomy infection (OPSI)can occur in 0.5% cases with a high mortality (>5 0 % ) [ 1 3 - 1 5 ] . This led the surgeons to attemptp reserving the spleen and avoid splenectomywhenever possible. Splenorrh a p h y, mesh splenorrh a p h yand partial splenectomy have been employed asmost common procedures of splenic salvage. In aretrospective review of splenic trauma in 1982,