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<strong>Tour</strong>-<strong>de</strong>-<strong>Force</strong>: Interplay between Mitochondria and Cell Cycle Progression Fall 2007ReferencesArticlesAlirol, E. and Martinou, JC. (2006) “Mitochondria and cancer: is there a morphological connection?”, Oncogene 25, 4706-4716.Arakaki, N et al. (2006) “Dynamics of Mitochondria during the Cell Cycle”, Biology and Pharmacology Bulletins 29, 1962-1965.Ashburner, M. and Bonnert, J.J. (1979) “The induction of gene activity in Drosophila by heat shock”, Cell 17, 241-254.Berg, J.M.; Tymoczko, J.L. and Stryer, L. (2006) Biochemistry, W.H. Freeman & Co Ltd., New YorkBlomen, V.A. and Boonstra, J. (2007) "Cell fate <strong>de</strong>termination during G1 phase progression" Cellular and Molecular Life Sciences,Published Online, 1-21.Bokko, P.B. et al. (2007) "Diverse Cytopathologies in Mitochondrial Disease Are Caused by AMP-activated Protein Kinase Signaling",Molecular Biology of the Cell 18, 1874-1886.Boom, R. et al. (1988) “Induction of gene expression un<strong>de</strong>r human cytomegalovirus immediate enhancer-promoter control byinhibition of protein synthesis is cell cycle <strong>de</strong>pen<strong>de</strong>nt”, Journal of General Virology 69, 1179-1193.Brand, K. et al. (1997) “Aerobic glycolysis by proliferating cells: protection against oxidative stress at the expense of energy yield”.Journal of Bioenergetics and Biomembranes 29, 355-364.Chen, H. and Chan, D. (2005) "Emerging functions of mammalian mitochondrial fusion and fission", Human Molecular Genetics 14,283-289.Cooper, G.M. and Hausman, R.E. (2007) “The Cell: A Molecular Approach”, Sinauer, 4 th ed.Cribbs, J. and Strack, S. (2007) “Reversible phosphorylation of Drp1 by cyclic AMP-<strong>de</strong>pen<strong>de</strong>nt protein kinase and calcineurinregulates mitochondrial fission and cell <strong>de</strong>ath”, EMBO Reports 8, 939-944.Desai; Myers; Schreiber, (2002), “FKBP12-Rapamycin-Associated Protein Associates with Mitochondria and Senses Osmotic Stressvia Mitochondrial Dysfunction”, Proceedings of the National Aca<strong>de</strong>my of Sciences of the United States of America (PNAS), 99, 4319-4324.Dorward, Sweet, Moorehead and Singh (1997) “Mitochondrial Contributions to Cancer Cell Physiology: Redox Balance, Cell Cycle,and Drug Resistance”, Journal of bioenergetics and biomembrane, 29, pp: 385-392.Fesik, S.W. and Shi, Y. (2001) "Controlling the caspases", Science 294, 5546.Frauwirth, K.A. and Thompson, C.B. (2004) “Regulation of T-lymphocyte metabolism”, The Journal of Immunology 172, 4661-4665.Hardie, D.G. (2005) "New roles for the LKB1->AMPK pathway", Current Opinion in Cell Biology 17, 167-173.Hardie, D. (2007) “AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy”, Nature Reviews 8, 774-785.Hawley, S. et al. (1996) “Characterization of the AMP-activated protein kinase from rat liver and i<strong>de</strong>ntification of threonine 172 as themajor site at which it phosphoylates AMP-activated protein kinase”, Journal of Biological Chemistry 271, 27879-27887.Hoppins, S. et al. (2007) “The machines that divi<strong>de</strong> and fuse Mitochondria”, Annual Reviews in Biochemistry 76, 751-780.Hue, L. et al. (2003) “AMP-activated protein kinase (AMPK) control of fatty acid and glucose metabolism in the ischemic heart”,Biochem. Soc. Trans. 31, 213-215.Hulleman, E. et al. (2004). “I<strong>de</strong>ntification of a restriction point at the G1/M transition in CHO cells”, Molecular Life Science, 61, 600-609.Hulleman, E. and Boonstra, J. (2000) “Regulation of G1 phase progression by growth factors and the extracellular matrix”, Cell. Mol.Life Sci. 58, 80-93.Huss, R. et al. (2000) “Quiescence of CD34-Negative hematopoietic stem cells is mediated by downregulation of Cyclin B and noStat activation”, Cytokine 12, 1195-1204.Hwang et al., (2004) “AMP-Activated Protein Kinase activity is required for vanadate-induced hypoxia-inducible factor 1α expressionin DU145 cells”, Carcinogenesis, 25, 2497-2507.Jones, R.G. et al. (2005) "AMP-Activated Protein Kinase induces a p53-<strong>de</strong>pen<strong>de</strong>nt metabolic checkpoint", Molecular Cell 18, 283-293.Kaushik, V.K. et al. (2001) "Regulation of fatty acid oxidation and glucose metabolism in rat soleus muscle: effects of AICAR" Am JPhysiol Endocrinol Metab 281, E335-E340.Kühn, et al. (1974) “Kinetic properties of the phosphofructokinase from erythrocytes of rats and rabbits. 2. The influence of effectorsun<strong>de</strong>r Nearly Cellular Conditions” European Journal of Biochemistry 43, 443-450.Kulawiec, M. et al. (2006) “Proteomics analysis of mitochondria-to-nucleus retrogra<strong>de</strong> response in human cancer”, Cancer Biology &Therapy 5, 967-975.Long, Y.C. et al. (2006). AMP-activated protein kinase signaling in metabolic regulation. Journal of Clinical Investigation 116, 1776.SCI 332 Advanced Molecular Cell Biology Research Proposal 54

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