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organisation - the Instituto Gulbenkian de Ciência

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NEUROMETRIC - PSYCHOMETRIC COMPARISON OF INTERVAL TIMING<br />

PERFORMANCE<br />

Tasks in which subjects must categorise sensory stimuli whose characteristics<br />

are parametrically varied have been powerful tools for relating neural processing<br />

to sensation in a rigorous and quantitative manner. We are applying <strong>the</strong><br />

same approach to an unconventional sensory modality, <strong>the</strong> ability to sense <strong>the</strong><br />

passage of time, by training rats on a two alternative forced choice interval<br />

timing task. We can <strong>de</strong>rive quantitative <strong>de</strong>scription of animals’ interval timing<br />

abilities via <strong>the</strong> fitting of psychometric functions to <strong>the</strong>ir choice data and <strong>the</strong>n<br />

compare this to <strong>the</strong> ability of neural activity to enco<strong>de</strong> <strong>the</strong> passage of time.<br />

A tight correspon<strong>de</strong>nce between <strong>the</strong> animals’ behavioural performance and <strong>the</strong><br />

neuronal encoding of time would suggest involvement of those neural signals<br />

in <strong>the</strong> process of timing.<br />

Thiago Gouvea has <strong>de</strong>signed <strong>the</strong> behavioural apparatus, programmed <strong>the</strong> behavioural<br />

control required for <strong>the</strong> task, and has trained four animals. We will<br />

soon be initiating neural recordings during task performance.<br />

IGC ANNUAL REPORT ‘11<br />

RESEARCH FELLOWS<br />

80

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