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organisation - the Instituto Gulbenkian de Ciência

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PORTUGUESE<br />

BIOINFORMATICS<br />

CENTRE<br />

Pedro Fernan<strong>de</strong>s (Eng) Head<br />

PhD in Biomedical Sciences, Universida<strong>de</strong> do Porto, Portugal, 2001<br />

Head of Facility since 2005<br />

link to facility website<br />

Head of IGC <strong>Gulbenkian</strong> Training Programme<br />

in Bioinformatics (GTPB)<br />

The CPB-RAP was created in 2005. It hosts Hermes, a mid size cluster that is<br />

<strong>de</strong>dicated to Bioinformatics. Access to this cluster is free but users need an<br />

account. This is a high performance platform, <strong>the</strong>refore more suitable for heavy<br />

computations than for trivial jobs. To make good use of this machine, applications<br />

usually require <strong>de</strong>ep modifications to allow for <strong>the</strong> use of <strong>the</strong> parallel<br />

processing capabilities. Most of <strong>the</strong> machine load is taken by lengthy simulation<br />

jobs for Population Genetics and by occasional orthologue searches using multiple<br />

BLAST jobs with pen domain software like InParanoid.<br />

PUBLIC ENGAGEMENT IN SCIENCE<br />

Talks for stu<strong>de</strong>nts, IGC, May, June<br />

MAJOR PROJECTS AND ACCOMPLISHMENTS<br />

• Assigning multi-site genotypes to <strong>the</strong>ir subpopulations;<br />

• PAS, a new data-mining method that flags statistically significant intercolumnar<br />

non-randomness of any complexity;<br />

• MultiLocus Sequence Typing using eBURST goeBURST and new methods;<br />

• MTBSS - Mycobacterium Tuberculosis Bioinformatic and Structural Strategies<br />

Towards Treatment - New Indigo - ERANET - Official start Sept 2010.<br />

EQUIPMENT AND INFRASTRUCTURE<br />

• IBM JS20 Bla<strong>de</strong> computer (60), and associated control, management and<br />

storage.<br />

Funding Fundação para a Ciência e a Tecnologia, Portugal<br />

IGC ANNUAL REPORT ‘11<br />

FACILITIES AND SERVICES<br />

99

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