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Treatment of First-episode Schizophrenia and Reducing Relapse: New and Emerging Treatment Options • Treatment of first-episode schizophrenia • Review of the anticipated new secondgeneration antipsychotics • Compare and contrast new and older second-generation antipsychotics in reducing relapse
Treatment of First-episode Schizophrenia Diana Perkins, MD, MPH Professor, Department of Psychiatry University of North Carolina at Chapel Hill Medical Director, Outreach and Support Intervention Services (OASIS) Chapel Hill, NC
Page 1 and 2: Across the Spectrum: Managing First
Page 3 and 4: Diana O. Perkins, MD, MPH Professor
Page 5 and 6: Outline • Achieving Appropriate a
Page 7 and 8: When to Diagnose? Progressive Stage
Page 9 and 10: When to Diagnose? Progressive Stage
Page 11: How to Diagnose? Domains of Psychos
Page 15 and 16: Stage-based Interventions Early Rec
Page 17 and 18: N-Acetyl Cysteine: Clinical Trial
Page 19 and 20: L-Theanine: Clinical Trial • Rati
Page 21 and 22: Cariprazine: Clinical Trial • Rat
Page 23 and 24: Paliperidone Palmitate versus Place
Page 25 and 26: Meta-analysis: Relapse Rates First
Page 27 and 28: Are Some Patients Harmed by Antipsy
Page 29 and 30: Do Antipsychotics Contribute to Gra
Page 31 and 32: Outline • Adherence in Schizophre
Page 33 and 34: Clinical Consequences of Nonadheren
Page 35 and 36: Suicide Attempts Increase When Ther
Page 37 and 38: Unfortunately, We Overestimate Adhe
Page 39 and 40: Reverberations from Adverse Effects
Page 41 and 42: Long-acting Injectable Antipsychoti
Page 43 and 44: Impact of Collaborative Care • Re
Page 45 and 46: Choosing an Antipsychotic: Switch o

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