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We Can Identify<br />
Risk Factors for Nonadherence<br />
These Can Differ for Each Patient<br />
Patient-related 1<br />
• Poor insight<br />
• Negative attitude<br />
toward medication<br />
• Prior nonadherence<br />
• Substance abuse<br />
• Cognitive impairment<br />
Treatment-related 1<br />
• Adverse effects<br />
• Lack of efficacy/<br />
continued symptoms<br />
Environment/Relationshiprelated<br />
1<br />
• Lack of family/social support<br />
• Problems with therapeutic alliance<br />
• Practical problems<br />
(financial, transportation, etc.)<br />
Societal-related 2<br />
• Stigma attached to illness<br />
• Stigma caused by medication<br />
adverse effects<br />
1. Velligan DI, et al. J Clin Psychiatry. 2009;70(suppl 4):1-46.<br />
2. Lee S, et al. Soc Sci Med. 2006;62(7):1685-1696.