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Long-acting Injectable Antipsychotics Lower Risk of Rehospitalization After First Hospitalization for Schizophrenia Any depot injection compared with equivalent oral formulation Adjusted Hazard Ratio Rehospitalization 95% CI P 0.36 0.17-0.75 .0007 Tiihonen J, et al. Am J Psychiatry. 2011;168:603-609.
Impact of Collaborative Care • Recovery of a normal life in the community • Reduce impairments, disabilities, and handicaps • Active family involvement • Build on patients’ strengths, interests, and capabilities • Integrate + coordinate services • Requires time, patience, and resilience Individualization of treatment is a fundamental pillar of rehabilitation. Littrell KH, et al. Psychiatr Ann. 1998;28(7):371-377.
Page 1 and 2: Across the Spectrum: Managing First
Page 3 and 4: Diana O. Perkins, MD, MPH Professor
Page 5 and 6: Outline • Achieving Appropriate a
Page 7 and 8: When to Diagnose? Progressive Stage
Page 9 and 10: When to Diagnose? Progressive Stage
Page 11 and 12: How to Diagnose? Domains of Psychos
Page 13 and 14: Treatment of First-episode Schizoph
Page 15 and 16: Stage-based Interventions Early Rec
Page 17 and 18: N-Acetyl Cysteine: Clinical Trial
Page 19 and 20: L-Theanine: Clinical Trial • Rati
Page 21 and 22: Cariprazine: Clinical Trial • Rat
Page 23 and 24: Paliperidone Palmitate versus Place
Page 25 and 26: Meta-analysis: Relapse Rates First
Page 27 and 28: Are Some Patients Harmed by Antipsy
Page 29 and 30: Do Antipsychotics Contribute to Gra
Page 31 and 32: Outline • Adherence in Schizophre
Page 33 and 34: Clinical Consequences of Nonadheren
Page 35 and 36: Suicide Attempts Increase When Ther
Page 37 and 38: Unfortunately, We Overestimate Adhe
Page 39 and 40: Reverberations from Adverse Effects
Page 41: Long-acting Injectable Antipsychoti
Page 45 and 46: Choosing an Antipsychotic: Switch o

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