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Choosing an Antipsychotic:<br />

Switch or Stay?<br />

• Past history of efficacy of drug response<br />

• Nature of psychiatric condition, acuity<br />

• Target signs and symptoms<br />

• Patient preference, history of adherence<br />

• Need for special monitoring<br />

• Amenable to other interventions to address tolerability?<br />

– Diet, exercise, and statins for obesity and dyslipidemia<br />

– Beta-blockers for akathisia<br />

– Anticholinergic medications for EPS

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