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44<br />

Ensuring eeuitable access to cost-effective medicines and technology<br />

anatomical therapeutic chemical -ATCcode).<br />

This involves price volume<br />

agreements whereby prices decrease as<br />

volume increase and all discounts are<br />

confidential. These agreements can be<br />

terminated with three months’ notice,<br />

which can then be used in the case of<br />

parallel imports.<br />

Assessing expensive medicines<br />

Another important initiative in Denmark<br />

that has benefited the centralized<br />

procurement work of Amgros is the<br />

Danish Council for the Use of Expensive<br />

Hospital Medicines (RADS council),<br />

established in 2010. The RADS council<br />

consists of representatives from each<br />

region, the National Health Board,<br />

the Danish Association of Clinical<br />

Pharmacology and the Patients’<br />

Association. The Council’s objective is<br />

to ensure that all patients have access<br />

to the best possible treatment no matter<br />

where they live and which hospital they<br />

visit. To achieve this, the RADS council<br />

set up smaller professional councils<br />

consisting of leading experts within the<br />

different specialties. Each professional<br />

council evaluates the clinical benefits<br />

of expensive medicines that have been<br />

selected for evaluation. The evaluation<br />

is based on dossiers submitted by the<br />

industry and an analysis of the literature<br />

of the therapeutic area. RADS uses the<br />

Grading of Recommendations Assessment<br />

(GRADE) methodology ‡ . After a thorough<br />

assessment, the professional council<br />

publishes recommendations for treatment.<br />

Amgros uses these recommendations for<br />

treatment to determine which medicines it<br />

will hold tenders for. The RADS council<br />

then prepares a priority list showing which<br />

generic substances hospitals should choose<br />

first, then second and so forth. After the<br />

tender, the recommendation includes the<br />

name of products.<br />

The results of the tender are used<br />

to establish a list of medicines that<br />

hospitals should use for the treatment in<br />

question. The winner of the tender and<br />

their product is ranked first on the list<br />

which prescribers will then use unless<br />

they have a justification not to. It is<br />

important to underline that physicians<br />

maintain their prescription authority.<br />

‡ http://www.gradeworkinggroup.org/index.htm<br />

The system was originally received<br />

negatively as not respecting physician’s<br />

autonomy. Over time, however, many<br />

physicians have started to regard the<br />

system as helpful § , and instead now see<br />

the treatment recommendations as a useful<br />

tool for decision making; the system is<br />

also reported to alleviate physicians’<br />

workloads.<br />

Prioritizing quality<br />

The RADS council has made it possible<br />

for Amgros to negotiate better prices.<br />

While an evaluation of the process to<br />

assess cost savings from engaging the<br />

RADS council is still pending and will<br />

depend on hospitals’ implementation of<br />

the tool, what is clear is that the RADS<br />

process has improved quality of treatment<br />

in Denmark. 1 Preliminary estimates<br />

suggest that the RADS council and its<br />

recommendations has given the country<br />

€42 million added value at an expense of<br />

approximately €22 million since 2010. 1<br />

Prioritizing cost-effective processes<br />

Over the 25 years that Amgros has<br />

existed, billions of Euros have been saved<br />

for Danish public hospitals. 1 Although<br />

the objective remains the same- to save<br />

costs in pharmaceutical procurement –<br />

Amgros has become more than a trading<br />

company. In addition to ensuring savings,<br />

Amgros has been able to promote safety<br />

and quality of medicines used in hospitals<br />

across Denmark and has also engaged in<br />

research and development activities by<br />

promoting research collaborations with<br />

hospital pharmacies. It also provides<br />

administrative support to hospital<br />

pharmacies, allowing them to focus more<br />

on patient care and their core tasks.<br />

Trading has been made easier for<br />

both suppliers and customers through<br />

Amgros. The specially tailored tender<br />

and Enterprise Resource Planning (ERP)<br />

systems support the business processes<br />

for hospital pharmacies, hearing clinics<br />

and suppliers. Hospital pharmacies and<br />

hearing clinics achieve considerable<br />

administrative savings by having Amgros<br />

organize supply, and fully integrating<br />

order management systems. The efficient<br />

§ This assessment is based on feedback from the RADS<br />

Secretary General.<br />

ERP systems also mean that Amgros<br />

does not have to manage and run stocks<br />

of medicines. Hospital pharmacies order<br />

drugs directly from the supplier-once<br />

approved through the tender processthrough<br />

an online ERP system.<br />

of Euros have<br />

been saved<br />

‘‘billions<br />

As a purchaser Amgros is constantly<br />

on the lookout for cheaper alternatives<br />

to existing medicines that are also of<br />

equivalent quality. Pharmacists in its<br />

tendering unit are employed to scan<br />

the market, make decisions about new<br />

products and explore possibilities for<br />

substitution or parallel import. Suppliers<br />

can benefit from the unique internetbased<br />

tendering system, which ensures<br />

easy workflows, transparency and<br />

equal treatment for everyone submitting<br />

a tender.<br />

Next steps<br />

Amgros will continue to play an important<br />

role in the centralized procurement<br />

for hospital medicines in Denmark. It<br />

continues to meet the regions’ expectations<br />

and reduces costs by working in close<br />

and constructive dialogue with all<br />

stakeholders. Amgros is driving an<br />

efficient business when it comes to buying<br />

pharmaceuticals. Centralized procurement<br />

has resulted in savings for Denmark and<br />

Amgros is now working on becoming a<br />

strategic procurement business partner.<br />

Being a strategic partner means being<br />

able to forecast market trends but also<br />

scanning the market for new products and<br />

innovations, known as horizon scanning.<br />

References<br />

1<br />

Internal data, Department of Business Analysis,<br />

Amgros.<br />

2<br />

KPMG. External Analysis of Pharmaceutical<br />

Procurement of Amgros. Copenhagen: Denmark,<br />

2014. Available in Danish upon request.<br />

Eurohealth — Vol.22 | No.2 | 2016

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