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Floor plan - 2013 Annual Meeting - American Association for Hand ...

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ASRM SCIENTIFIC PAPER PRESENTATIONS:<br />

HEAD AND NECK<br />

The Incidence of Venous Thromboembolism in Head and Neck Reconstruction<br />

Institution where the work was prepared: Memorial Sloan-Kettering Cancer Center, New York, NY, USA<br />

Constance M. Chen, MD, MPH; Joseph J. Disa; Babak J. Mehrara; Memorial Sloan-Kettering Cancer Center<br />

BACKGROUND:<br />

Cancer patients undergoing head and neck reconstruction are at high risk <strong>for</strong> venous thromboembolism (VTE). Such patients often<br />

exhibit major risk factors including advanced age, immobility due to a prolonged surgical procedure, malignant disease, and hypercoagulability.<br />

Currently, no published data exist regarding the incidence of VTE in patients undergoing oncologic head and neck reconstruction.<br />

This study evaluates the incidence of symptomatic pulmonary embolism (PE) and deep venous thrombosis (DVT) after head<br />

and neck reconstruction at a single tertiary-care cancer center.<br />

METHODS:<br />

A retrospective review was done of 6759 surgical procedures per<strong>for</strong>med between 1997 and 2006 at Memorial Sloan-Kettering Cancer<br />

Center (MSKCC). Data from a prospectively maintained surgical database was reviewed to identify procedures that resulted in postoperative<br />

PE or DVT.<br />

RESULTS:<br />

From 1997-2006, there were 6759 procedures per<strong>for</strong>med by two surgeons at MSKCC. There were 1583 head and neck operations<br />

(n=1583) and 5176 non-head and neck procedures (n=5176). Non-head and neck procedures included surgeries of the breast, upper<br />

extremity, lower extremity, trunk, and back. When compared to patients undergoing procedures in other parts of the body, patients<br />

undergoing oncologic head and neck reconstruction were older, spent more days in the hospital, and underwent longer anesthesia<br />

times. While the incidence of VTE was less than 1% in both patient populations, there was a six-fold greater incidence of VTE among<br />

patients undergoing head and neck surgery (0.57%) than non-head and neck surgeries (0.09%). The difference between the two groups<br />

was statistically significant (p = 0.001).<br />

CONCLUSIONS:<br />

The incidence of pulmonary embolism was significantly higher in cancer patients undergoing head and neck reconstructions than in all<br />

other types of procedures. Possible reasons include advanced age and prolonged immobility. When possible, anticoagulant therapy<br />

<strong>for</strong> prophylaxis against VTE in cancer patients undergoing head and neck reconstruction is strongly recommended.<br />

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