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1- Haemostatic Mechanism3

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➢ The platelet contains three types of storage granules: dense, α and

lysosomes. The more frequent specific α granules contain clotting

factors, VWF, platelet‐derived growth factor (PDGF) and other

proteins.

➢Dense granules are less common and contain adenosine

diphosphate (ADP), adenosine triphosphate (ATP), serotonin and

calcium.

➢Lysosomes contain hydrolytic enzymes.

➢Platelets are also rich in signalling and cytoskeletal proteins,

which support the rapid switch from quiescence to activation that

follows vessel damage.

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