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1- Haemostatic Mechanism3

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➢During the release reaction, the contents of the granules are

discharged into the open canalicular system.

Platelet antigens

Several platelet surface proteins have been found to be important

antigens in platelet‐specific autoimmunity and they have been

termed human platelet antigens (HPA).

In most cases,two different alleles exist, termed a or b alleles (e.g.

HPA‐1a).Platelets also express ABO and human leucocyte antigen

(HLA) class I but not class II antigens.

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