21.02.2020 Views

1- Haemostatic Mechanism3

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

activates factor XI and XIII and cofactors V and VIII.

The fibrin component of the haemostatic plug increases as the

fused platelets completely degranulate and autolyse, and after a

few hours the entire haemostatic plug is transformed into a solid

mass of crosslinked fibrin.

because of incorporation of plasminogen (tissue plasminogen

activator TPA)which is produced by endothelial cells, this plug

begins to autodigest during the same time frame (activate

fibrinolysis).

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!