1- Haemostatic Mechanism3
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The action of protein C is enhanced by another vitamin K‐
dependent protein S, which binds protein C to the platelet surface
(Fig. 24.13). Also protein C bind to its receptor on the endothelial
surface, promoting protein C activation by the thrombin–
thrombomodulin complex.
In addition, activated protein C enhances fibrinolysis (Fig. 24.13).
like other serine proteases, activated protein C is inactivated by
serum protease inactivators (serpins), e.g. antithrombin.