Ohio Nurse - June 2021
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Page 22 <strong>Ohio</strong> <strong>Nurse</strong> <strong>June</strong> <strong>2021</strong><br />
COVID-19 Vaccinations:<br />
Knowledge vs. Myth to Get Back to A New Normal<br />
Erin Morgan, DNP, FNP-BC<br />
Reprinted with permission from<br />
Tennessee <strong>Nurse</strong> May <strong>2021</strong> issue<br />
In Tennessee, the COVID-19 virus has infected<br />
826,371 people, and 12,022 individuals have lost<br />
their lives as of April 13, <strong>2021</strong>. The virus has become<br />
the third leading cause of death in the United States<br />
for 2020. Now that multiple vaccinations are more<br />
widely available, nurses can educate the public<br />
about their options and dispel the myths surrounding<br />
these important tools to decrease future COVID-19<br />
infections and deaths. <strong>Nurse</strong>s have remained the<br />
most trusted profession throughout the pandemic,<br />
and therefore, must use this position to inform the<br />
public about their vaccine options. Understandably,<br />
individuals may remain hesitant to obtain a new<br />
vaccine when they still have unanswered questions.<br />
<strong>Nurse</strong>s have always provided detailed education to<br />
allow individuals to make the most informed choice<br />
for their health. Information surrounding COVID-19<br />
vaccination is no different.<br />
Vaccine Options<br />
Currently, there are three COVID-19 vaccines<br />
approved for emergency use authorization<br />
(EUA) in the United States, two-dose Pfizer or<br />
Moderna Vaccines and the single-dose Johnson<br />
and Johnson-Janseen vaccine. <strong>Nurse</strong>s should<br />
recommend individuals receive any vaccine that<br />
is available to them. The FDA has deemed all of<br />
the vaccines safe and effective to prevent infection<br />
and severe complications from COVID-19. This<br />
recommendation applies to all individuals, not just<br />
those who have co-morbidities. As more individuals<br />
are vaccinated against the virus, the number of<br />
available individuals COVID-19 can reside continues<br />
to decrease.<br />
mRNA Vaccines<br />
The Pfizer vaccine was first approved for use in<br />
December 2020, with the Moderna vaccine approval<br />
following shortly after. Both vaccines require two<br />
doses; 21 days between Pfizer doses and 28 days<br />
between Moderna doses.<br />
These two vaccines use messenger RNA to<br />
provide COVID-19 immunity. This mRNA technology<br />
has been studied for years and has already been<br />
used in some cancer treatments. These vaccines<br />
use mRNA to instruct cells to make a ‘spike protein’<br />
similar to that of the COVID-19 virus. The recipient’s<br />
immune system responds to these new proteins by<br />
making antibodies. These new antibodies remain<br />
with the recipient to recognize the similar ‘spike<br />
protein’ if a COVID-19 infection occurs. The mRNA<br />
does not change the vaccine recipient’s DNA;<br />
instead, it trains the immune system how to respond<br />
if the virus is encountered.<br />
Side effects for the Pfizer and Moderna vaccines<br />
include pain or swelling at the vaccine site, fever,<br />
muscle aches, fatigue, or headache. These<br />
symptoms may occur after the first or second dose.<br />
Individuals who have had COVID-19 may have<br />
more side effects with the first dose. However, many<br />
individuals who have not had COVID-19 report more<br />
side effects after a second dose.<br />
Viral Vector Vaccine<br />
The Johnson and Johnson-Janssen vaccine is<br />
the most recent to receive approval. This vaccine<br />
is a single-dose injection that offers convenience<br />
and expediency compared to the other two vaccine<br />
options. This vaccine was tested later during the<br />
pandemic resulting in differing effectiveness data that<br />
should not be compared to the Pfizer or Moderna<br />
vaccines. Additionally, the Johnson and Johnson-<br />
Janssen vaccine was tested in locations where<br />
variants of COVID-19 were already circulating,<br />
affecting results of the study. The use of this vaccine<br />
was paused to examine six blood clotting events in<br />
women. Nevertheless, the Johnson and Johnson-<br />
Janssen vaccine has already been received by<br />
millions of individuals to date.<br />
The Johnson and Johnson-Janssen vaccine<br />
provides immunity through a viral vector instead<br />
of mRNA. Viral Vectors, non-infectious harmless<br />
viruses, are used to transmit information to the<br />
recipient’s immune system. The vector instructs<br />
the recipients’ immune system how to produce<br />
antibodies for the ‘spike protein’ recognizable on the<br />
COVID-19 virus. While considered effective after two<br />
weeks per the CDC, immunity increases up to 28<br />
days past the single dose. Viral vector vaccines have<br />
already been used to treat cancer and the Ebola<br />
virus.<br />
Side effects are similar to the previous two<br />
vaccines and include pain or swelling at the vaccine<br />
site, fever, muscle aches, fatigue, or headache. The<br />
CDC recommends that women between the ages<br />
of 18-50 who receive the Johnson and Johnson-<br />
Janssen vaccine should be aware of the rare but<br />
increased risk of thrombocytopenia syndrome. Any<br />
individual who feels uncomfortable with this risk is<br />
recommended to obtain one of the other two vaccine<br />
options.<br />
Vaccine Hesitancy<br />
Many patients and fellow nurses have questions<br />
and concerns about these new vaccinations.<br />
These apprehensions are valid and may take time<br />
to overcome. One way to dispel myths and answer<br />
questions surrounding these vaccines is to provide<br />
evidence-based education from trusted sources and<br />
then let the patient or nurse choose for themselves.<br />
The process was rushed<br />
All medications and vaccines must go through<br />
an approval process with the FDA. All three<br />
vaccinations currently approved have undergone this<br />
process and received emergency use authorization<br />
(EUA). This approval does not mean that the steps<br />
for approval were shortened or skipped; instead,<br />
it provides approval for widespread use in the<br />
pandemic when benefit is demonstrated.<br />
Scientists were able to accelerate the<br />
development of these vaccines due to several<br />
factors. Scientists shared information between<br />
countries and between companies in an<br />
unprecedented effort to roll out multiple COVID-19<br />
vaccine options at once. Cooperation occurred in<br />
the scientific community using methods that were<br />
already in progress, such as viral vector and mRNA<br />
technology, developed for a new purpose. Moreover,<br />
governments provided funding to help cover costs<br />
for the development of vaccines locally and abroad;<br />
in the United States, this was titled “Operation<br />
Warp Speed.” Additionally, many volunteers of<br />
varying ages and races enrolled in the vaccine trials<br />
decreasing the time to find participants. Finally,<br />
vaccine developers were able to move through the<br />
phases of vaccine development promptly. Phase<br />
3 trials were completed relatively quickly due to the<br />
infectious and widespread nature of COVID-19,<br />
when many participants were exposed, proving<br />
effectiveness. All of these factors allowed multiple<br />
vaccines to be developed in a time of great need.<br />
Millions of individuals have received all three<br />
vaccines with few severe side effects. Extensive<br />
monitoring continues for each vaccine, which makes<br />
these vaccines the most scrutinized in recent history.<br />
During this writing, Johnson and Johnson- Janssen<br />
vaccine distribution was paused to examine the<br />
data for six patients who developed blood clots.<br />
The pause was brief; however, the examination<br />
demonstrates the ongoing commitment to safety<br />
surrounding these vaccines. It is understandable<br />
for individuals to have questions about a strongly<br />
recommended new therapy. Providing answers<br />
and resources to individuals who express concerns<br />
about the unprecedented process may alleviate their<br />
concerns.<br />
I’m healthy and don’t need it<br />
It is recommended that all individuals receive<br />
the COVID-19 vaccine when it is available to them.<br />
The risks associated with COVID-19 are higher than<br />
the risk associated with any side effects from the<br />
vaccine at this time, even for those who are young<br />
and healthy. Each time an individual becomes sick<br />
with COVID-19, there is a risk of severe disease to<br />
themselves and passing it along to others around<br />
them who can also become seriously ill. Vaccination<br />
is the safest way to obtain immunity to COVID-19 at<br />
this time. As more individuals become immunized,<br />
the virus will have fewer places to spread,<br />
decreasing overall illness and allowing a return to<br />
normal.<br />
I had COVID and don’t need the vaccine<br />
Scientists continue to study how long immunity<br />
to the disease lasts after a COVID-19 infection.<br />
While rare, it is possible individuals can become reinfected<br />
with the virus. Individuals who previously<br />
had COVID-19 may notice some side effects with the<br />
first dose of the two-dose Pfizer or Moderna series;<br />
however, most side effects remain mild. Each time<br />
an individual becomes sick with COVID-19, there is<br />
a risk of severe disease, long-term health effects,<br />
and spreading the disease to others who can also<br />
become significantly ill.<br />
Conclusion<br />
Tennessee’s quickest way to emerge from<br />
this pandemic is through public health measures<br />
nurses have pioneered for years: vaccinations,<br />
handwashing, and education. <strong>Nurse</strong>s themselves<br />
may have concerns and questions about receiving<br />
a vaccine after a year of difficulty and division.<br />
Conversations about COVID-19 vaccines should be<br />
held in a spirit of acceptance and inquiry, allowing<br />
individuals to ask questions and feel comfortable<br />
about the choices they are making for themselves.<br />
Shaming and embarrassing individuals will only<br />
foster ongoing resistance and suspicion. Instead,<br />
nurses should focus on the benefits of vaccination:<br />
A quicker return to normal, protection of patients and<br />
loved ones, and the ability to gather with others who<br />
are vaccinated without masks.<br />
Reference websites for nurses:<br />
- https://covidvaccinefacts4nurses.org/<br />
- https://www.cdc.gov/coronavirus/2019-ncov/<br />
vaccines/vaccine-benefits.html<br />
- https://www.hopkinsmedicine.org/health/<br />
conditions-and-diseases/coronavirus/is-thecovid19-vaccine-safe<br />
References available upon request.<br />
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