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Ohio Nurse - June 2021

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Page 22 <strong>Ohio</strong> <strong>Nurse</strong> <strong>June</strong> <strong>2021</strong><br />

COVID-19 Vaccinations:<br />

Knowledge vs. Myth to Get Back to A New Normal<br />

Erin Morgan, DNP, FNP-BC<br />

Reprinted with permission from<br />

Tennessee <strong>Nurse</strong> May <strong>2021</strong> issue<br />

In Tennessee, the COVID-19 virus has infected<br />

826,371 people, and 12,022 individuals have lost<br />

their lives as of April 13, <strong>2021</strong>. The virus has become<br />

the third leading cause of death in the United States<br />

for 2020. Now that multiple vaccinations are more<br />

widely available, nurses can educate the public<br />

about their options and dispel the myths surrounding<br />

these important tools to decrease future COVID-19<br />

infections and deaths. <strong>Nurse</strong>s have remained the<br />

most trusted profession throughout the pandemic,<br />

and therefore, must use this position to inform the<br />

public about their vaccine options. Understandably,<br />

individuals may remain hesitant to obtain a new<br />

vaccine when they still have unanswered questions.<br />

<strong>Nurse</strong>s have always provided detailed education to<br />

allow individuals to make the most informed choice<br />

for their health. Information surrounding COVID-19<br />

vaccination is no different.<br />

Vaccine Options<br />

Currently, there are three COVID-19 vaccines<br />

approved for emergency use authorization<br />

(EUA) in the United States, two-dose Pfizer or<br />

Moderna Vaccines and the single-dose Johnson<br />

and Johnson-Janseen vaccine. <strong>Nurse</strong>s should<br />

recommend individuals receive any vaccine that<br />

is available to them. The FDA has deemed all of<br />

the vaccines safe and effective to prevent infection<br />

and severe complications from COVID-19. This<br />

recommendation applies to all individuals, not just<br />

those who have co-morbidities. As more individuals<br />

are vaccinated against the virus, the number of<br />

available individuals COVID-19 can reside continues<br />

to decrease.<br />

mRNA Vaccines<br />

The Pfizer vaccine was first approved for use in<br />

December 2020, with the Moderna vaccine approval<br />

following shortly after. Both vaccines require two<br />

doses; 21 days between Pfizer doses and 28 days<br />

between Moderna doses.<br />

These two vaccines use messenger RNA to<br />

provide COVID-19 immunity. This mRNA technology<br />

has been studied for years and has already been<br />

used in some cancer treatments. These vaccines<br />

use mRNA to instruct cells to make a ‘spike protein’<br />

similar to that of the COVID-19 virus. The recipient’s<br />

immune system responds to these new proteins by<br />

making antibodies. These new antibodies remain<br />

with the recipient to recognize the similar ‘spike<br />

protein’ if a COVID-19 infection occurs. The mRNA<br />

does not change the vaccine recipient’s DNA;<br />

instead, it trains the immune system how to respond<br />

if the virus is encountered.<br />

Side effects for the Pfizer and Moderna vaccines<br />

include pain or swelling at the vaccine site, fever,<br />

muscle aches, fatigue, or headache. These<br />

symptoms may occur after the first or second dose.<br />

Individuals who have had COVID-19 may have<br />

more side effects with the first dose. However, many<br />

individuals who have not had COVID-19 report more<br />

side effects after a second dose.<br />

Viral Vector Vaccine<br />

The Johnson and Johnson-Janssen vaccine is<br />

the most recent to receive approval. This vaccine<br />

is a single-dose injection that offers convenience<br />

and expediency compared to the other two vaccine<br />

options. This vaccine was tested later during the<br />

pandemic resulting in differing effectiveness data that<br />

should not be compared to the Pfizer or Moderna<br />

vaccines. Additionally, the Johnson and Johnson-<br />

Janssen vaccine was tested in locations where<br />

variants of COVID-19 were already circulating,<br />

affecting results of the study. The use of this vaccine<br />

was paused to examine six blood clotting events in<br />

women. Nevertheless, the Johnson and Johnson-<br />

Janssen vaccine has already been received by<br />

millions of individuals to date.<br />

The Johnson and Johnson-Janssen vaccine<br />

provides immunity through a viral vector instead<br />

of mRNA. Viral Vectors, non-infectious harmless<br />

viruses, are used to transmit information to the<br />

recipient’s immune system. The vector instructs<br />

the recipients’ immune system how to produce<br />

antibodies for the ‘spike protein’ recognizable on the<br />

COVID-19 virus. While considered effective after two<br />

weeks per the CDC, immunity increases up to 28<br />

days past the single dose. Viral vector vaccines have<br />

already been used to treat cancer and the Ebola<br />

virus.<br />

Side effects are similar to the previous two<br />

vaccines and include pain or swelling at the vaccine<br />

site, fever, muscle aches, fatigue, or headache. The<br />

CDC recommends that women between the ages<br />

of 18-50 who receive the Johnson and Johnson-<br />

Janssen vaccine should be aware of the rare but<br />

increased risk of thrombocytopenia syndrome. Any<br />

individual who feels uncomfortable with this risk is<br />

recommended to obtain one of the other two vaccine<br />

options.<br />

Vaccine Hesitancy<br />

Many patients and fellow nurses have questions<br />

and concerns about these new vaccinations.<br />

These apprehensions are valid and may take time<br />

to overcome. One way to dispel myths and answer<br />

questions surrounding these vaccines is to provide<br />

evidence-based education from trusted sources and<br />

then let the patient or nurse choose for themselves.<br />

The process was rushed<br />

All medications and vaccines must go through<br />

an approval process with the FDA. All three<br />

vaccinations currently approved have undergone this<br />

process and received emergency use authorization<br />

(EUA). This approval does not mean that the steps<br />

for approval were shortened or skipped; instead,<br />

it provides approval for widespread use in the<br />

pandemic when benefit is demonstrated.<br />

Scientists were able to accelerate the<br />

development of these vaccines due to several<br />

factors. Scientists shared information between<br />

countries and between companies in an<br />

unprecedented effort to roll out multiple COVID-19<br />

vaccine options at once. Cooperation occurred in<br />

the scientific community using methods that were<br />

already in progress, such as viral vector and mRNA<br />

technology, developed for a new purpose. Moreover,<br />

governments provided funding to help cover costs<br />

for the development of vaccines locally and abroad;<br />

in the United States, this was titled “Operation<br />

Warp Speed.” Additionally, many volunteers of<br />

varying ages and races enrolled in the vaccine trials<br />

decreasing the time to find participants. Finally,<br />

vaccine developers were able to move through the<br />

phases of vaccine development promptly. Phase<br />

3 trials were completed relatively quickly due to the<br />

infectious and widespread nature of COVID-19,<br />

when many participants were exposed, proving<br />

effectiveness. All of these factors allowed multiple<br />

vaccines to be developed in a time of great need.<br />

Millions of individuals have received all three<br />

vaccines with few severe side effects. Extensive<br />

monitoring continues for each vaccine, which makes<br />

these vaccines the most scrutinized in recent history.<br />

During this writing, Johnson and Johnson- Janssen<br />

vaccine distribution was paused to examine the<br />

data for six patients who developed blood clots.<br />

The pause was brief; however, the examination<br />

demonstrates the ongoing commitment to safety<br />

surrounding these vaccines. It is understandable<br />

for individuals to have questions about a strongly<br />

recommended new therapy. Providing answers<br />

and resources to individuals who express concerns<br />

about the unprecedented process may alleviate their<br />

concerns.<br />

I’m healthy and don’t need it<br />

It is recommended that all individuals receive<br />

the COVID-19 vaccine when it is available to them.<br />

The risks associated with COVID-19 are higher than<br />

the risk associated with any side effects from the<br />

vaccine at this time, even for those who are young<br />

and healthy. Each time an individual becomes sick<br />

with COVID-19, there is a risk of severe disease to<br />

themselves and passing it along to others around<br />

them who can also become seriously ill. Vaccination<br />

is the safest way to obtain immunity to COVID-19 at<br />

this time. As more individuals become immunized,<br />

the virus will have fewer places to spread,<br />

decreasing overall illness and allowing a return to<br />

normal.<br />

I had COVID and don’t need the vaccine<br />

Scientists continue to study how long immunity<br />

to the disease lasts after a COVID-19 infection.<br />

While rare, it is possible individuals can become reinfected<br />

with the virus. Individuals who previously<br />

had COVID-19 may notice some side effects with the<br />

first dose of the two-dose Pfizer or Moderna series;<br />

however, most side effects remain mild. Each time<br />

an individual becomes sick with COVID-19, there is<br />

a risk of severe disease, long-term health effects,<br />

and spreading the disease to others who can also<br />

become significantly ill.<br />

Conclusion<br />

Tennessee’s quickest way to emerge from<br />

this pandemic is through public health measures<br />

nurses have pioneered for years: vaccinations,<br />

handwashing, and education. <strong>Nurse</strong>s themselves<br />

may have concerns and questions about receiving<br />

a vaccine after a year of difficulty and division.<br />

Conversations about COVID-19 vaccines should be<br />

held in a spirit of acceptance and inquiry, allowing<br />

individuals to ask questions and feel comfortable<br />

about the choices they are making for themselves.<br />

Shaming and embarrassing individuals will only<br />

foster ongoing resistance and suspicion. Instead,<br />

nurses should focus on the benefits of vaccination:<br />

A quicker return to normal, protection of patients and<br />

loved ones, and the ability to gather with others who<br />

are vaccinated without masks.<br />

Reference websites for nurses:<br />

- https://covidvaccinefacts4nurses.org/<br />

- https://www.cdc.gov/coronavirus/2019-ncov/<br />

vaccines/vaccine-benefits.html<br />

- https://www.hopkinsmedicine.org/health/<br />

conditions-and-diseases/coronavirus/is-thecovid19-vaccine-safe<br />

References available upon request.<br />

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